Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPB1 | P04792 | 6/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31009402 | 0.90 | HSPB1 (0.63) | HSPB1TDP1ATMALDH1A1MAPK14 | |
| SCHEMBL24750210 | 0.90 | HSPB1 (0.63) | HSPB1TDP1ATMALDH1A1MAPK14 | |
| SCHEMBL16792585 | 0.83 | ALDH1A1 (0.49) | HSPB1TDP1ATMALDH1A1L3MBTL1 | |
| SCHEMBL221284 | 0.82 | ALDH1A1 (0.61) | HSPB1TDP1ATMALDH1A1L3MBTL1 | |
| SCHEMBL29588929 | 0.82 | ALDH1A1 (0.61) | HSPB1TDP1ATMALDH1A1L3MBTL1 | |
| SCHEMBL10817393 | 0.82 | ALDH1A1 (0.56) | TDP1ALDH1A1L3MBTL1HTTMAPT | |
| SCHEMBL3488024 | 0.82 | HSPB1 (0.59) | HSPB1TDP1ATMALDH1A1MAPK14 | |
| SCHEMBL4851442 | 0.81 | TDP1 (0.65) | HSPB1TDP1ATMALDH1A1L3MBTL1 | |
| SCHEMBL31009371 | 0.81 | HSPB1 (0.53) | HSPB1TDP1ATMALDH1A1L3MBTL1 | |
| SCHEMBL24750229 | 0.81 | HSPB1 (0.53) | HSPB1TDP1ATMALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109384784-B | Sulfonamide derivative, preparation method thereof and application thereof in medicine | 浙江海正药业股份有限公司 | 2021-01-12 | — | — | CN | disclosed |