SCHEMBL28501109

SCHEMBL28501109

CCCC1CCCC1.Sc1cccs1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.42
RAB9A P51151 3/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
HPGD P15428 2/20 0.40
CYP1A2 P05177 1/20 0.37
BCHE P06276 4/20 0.34
CHRNA7 P36544 1/20 0.33
ALDH1A1 P00352 2/20 0.33
ACHE P22303 1/20 0.33
CHRM3 P20309 1/20 0.33
KDM4E B2RXH2 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
HDAC3 O15379 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
OPRM1 P35372 1/20 0.32
OPRL1 P41146 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiophene SCHEMBL29272688 0.74 CYP1A2 (0.50) NPC1RAB9AL3MBTL1HPGDCYP1A2
Butylcyclohexane SCHEMBL27978634 0.73 CYP1A2 (0.55) NPC1RAB9AL3MBTL1MEN1KMT2A
SCHEMBL28514384 0.73 CYP1A2 (0.39) NPC1RAB9AL3MBTL1MEN1KMT2A
SCHEMBL28308031 0.72 CYP2C9 (0.43) NPC1RAB9AL3MBTL1MEN1KMT2A
SCHEMBL28861910 0.72 CYP1A2 (0.49) NPC1RAB9AL3MBTL1MEN1KMT2A
SCHEMBL128592 0.71
SCHEMBL139805 0.71
SCHEMBL9957872 0.71 FBP1 (0.41) NPC1RAB9AL3MBTL1MEN1KMT2A
SCHEMBL27775112 0.69
SCHEMBL23227948 0.69 CYP1A2 (0.62) MEN1KMT2ACYP1A2ALDH1A1OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109970768-B Based on carbazole eleven-membered condensed ring planar nucleus D (A-Ar)2Organic photoelectric compound, preparation method and application 常州大学 2020-12-25 CN disclosed