SCHEMBL28514384

SCHEMBL28514384

CCCC1CCCC1.CCCC[Sn](CCCC)(CCCC)c1cccs1

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.39
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
HPGD P15428 1/20 0.35
BCHE P06276 13/20 0.35
ACHE P22303 1/20 0.34
CHRNA7 P36544 1/20 0.32
PDE4A P27815 1/20 0.31
PDE4B Q07343 1/20 0.31
PDE4C Q08493 1/20 0.31
PDE4D Q08499 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28716563 0.92 CYP1A2 (0.42) CYP1A2NPC1RAB9AL3MBTL1MEN1
SCHEMBL275321 0.83 HDAC3 (0.36) CYP1A2L3MBTL1MEN1KMT2AHPGD
SCHEMBL5915087 0.83 HDAC3 (0.36) CYP1A2L3MBTL1MEN1KMT2AHPGD
SCHEMBL14889184 0.82 ALDH1A1 (0.36) NPC1RAB9AL3MBTL1
Octane SCHEMBL1164389 0.80 HDAC1 (0.39) CYP1A2NPC1RAB9AL3MBTL1MEN1
Thiophene SCHEMBL2762416 0.77 HDAC3 (0.33)
SCHEMBL15375290 0.77 HDAC1 (0.39) CYP1A2NPC1RAB9AL3MBTL1MEN1
Acetaldehyde SCHEMBL591968 0.76 HTT (0.35) CYP1A2L3MBTL1
Ethylene Glycol SCHEMBL28574191 0.74 HDAC3 (0.36) NPC1RAB9AL3MBTL1KMT2A
SCHEMBL28501109 0.73 NPC1 (0.42) CYP1A2NPC1RAB9AL3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109970768-B Based on carbazole eleven-membered condensed ring planar nucleus D (A-Ar)2Organic photoelectric compound, preparation method and application 常州大学 2020-12-25 CN disclosed