Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | DRD1 | P21728 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29620625 | 1.00 | CYP3A4 (0.52) | CYP3A4TDP1ALOX15SMN1; SMN2CASP1 | |
| Iodide SCHEMBL8511390 | 0.98 | CYP3A4 (0.50) | CYP3A4TDP1ALOX15SMN1; SMN2CASP1 | |
| Bromide SCHEMBL17963057 | 0.98 | CYP3A4 (0.50) | CYP3A4TDP1ALOX15SMN1; SMN2CASP1 | |
| SCHEMBL9324946 | 0.95 | CYP3A4 (0.52) | CYP3A4TDP1ALOX15SMN1; SMN2CASP1 | |
| SCHEMBL31193487 | 0.84 | CYP3A4 (0.46) | CYP3A4TDP1ALOX15SMN1; SMN2CASP1 | |
| SCHEMBL3064055 | 0.84 | CYP3A4 (0.53) | CYP3A4TDP1ALOX15SMN1; SMN2CASP1 | |
| SCHEMBL30842821 | 0.82 | ALDH1A1 (0.54) | CYP3A4TDP1ALOX15SMN1; SMN2CASP1 | |
| SCHEMBL30842815 | 0.82 | ALDH1A1 (0.54) | CYP3A4TDP1ALOX15SMN1; SMN2CASP1 | |
| SCHEMBL29230460 | 0.82 | ALDH1A1 (0.54) | CYP3A4TDP1ALOX15SMN1; SMN2CASP1 | |
| SCHEMBL150139 | 0.81 | TDP1 (0.69) | CYP3A4TDP1ESR1ESR2DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116199716-A | Chiral P, N, N ligand and preparation and application thereof | 中国科学院大连化学物理研究所 | 2023-06-02 | — | — | CN | claimed |
| US-8436111-B2 | Nickel catalyst system for the preparation of high CIS polybutadiene | BRIDGESTONE CORPORATION (JP) | 2013-05-07 | — | — | US | claimed |
| CN-116199716-A | Chiral P, N, N ligand and preparation and application thereof | 中国科学院大连化学物理研究所 | 2023-06-02 | — | — | CN | disclosed |
| CN-116199716-A | Chiral P, N, N ligand and preparation and application thereof | 中国科学院大连化学物理研究所 | 2023-06-02 | — | — | CN | disclosed |
| EP-3700914-A1 | HYDROGENATION OF CARBONYLS WITH TETRADENTATE PNNP LIGAND RUTHENIUM COMPLEXES | Firmenich SA (CH) | 2020-09-02 | — | — | EP | disclosed |
| CN-111417644-A | Hydrogenation of carbonyl groups using tetradentate PNNP ligand ruthenium complexes | 弗门尼舍有限公司 | 2020-07-14 | — | — | CN | disclosed |
| CN-107207546-B | Ligand component, related reaction product, activated reaction product, composition containing same and preparation method thereof | 美国陶氏有机硅公司 | 2020-06-09 | — | — | CN | disclosed |
| CN-108794527-B | Bidentate phosphine ligand and application thereof in hydroformylation reaction | 南京诚志清洁能源有限公司 | 2020-05-12 | — | — | CN | disclosed |
| CN-108586530-B | Bidentate phosphine ligand and its application in hydroformylation reaction | 南京诚志清洁能源有限公司 | 2020-05-12 | — | — | CN | disclosed |
| WO-2019175158-A1 | HYDROGENATION OF CARBONYLS WITH TETRADENTATE PNNP LIGAND RUTHENIUM COMPLEXES | FIRMENICH SA (CH) | 2019-09-19 | — | — | WO | disclosed |
| US-10179331-B2 | Ligand based chromium catalyst and application in catalyzing ethylene oligomerization | CHINA PETROLEUM & CHEIMCAL CORPORATION (CN) | 2019-01-15 | — | — | US | disclosed |
| EP-1426385-A1 | CATALYST FOR POLYMERIZATION OR COPOLYMERIZATION OF OLEFINS, PREPARATION AND USE OF THE SAME | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2004-06-09 | — | — | EP | disclosed |
| CN-1098269-C | Process for synthesizing water-soluble P-N bidental ligand and its application in preparing high-carbon aldehyde | CHINA PETROCHEMICAL CORP (CN) | 2003-01-08 | — | — | CN | disclosed |
| CN-1332182-A | Catalyst for polymerization and copolymerization of olefine and its synthesis and use | SHANGHAI INST ORGANIC CHEM (CN) | 2002-01-23 | — | — | CN | disclosed |
| US-6307067-B1 | Palladium and boron co-catalyzed addition of oxygen nucleophiles to vinyl epoxides | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2001-10-23 | — | — | US | disclosed |
| EP-1112240-A1 | THE ADDITION OF OXYGEN NUCLEOPHILES TO VINYL EPOXIDES | The Board of Trustees of The Leland S. Stanford Junior University (US) | 2001-07-04 | — | — | EP | disclosed |
| CN-1283626-A | Process for synthesizing water-soluble P-N bidental ligand and its application in preparing high-carbon aldehyde | CHINA PETROCHEMICAL CORP (CN) | 2001-02-14 | — | — | CN | disclosed |
| WO-2000014033-A1 | THE ADDITION OF OXYGEN NUCLEOPHILES TO VINYL EPOXIDES | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2000-03-16 | — | — | WO | disclosed |
| EP-0218100-B1 | CONJUGATED ALKADIENE TELOMERIZATION TO ORGANO-OXYALKADIENES | QUANTUM CHEMICAL CORPORATION (a Virginia corp.) (US) | 1989-11-29 | — | — | EP | disclosed |
| EP-0218100-A1 | Conjugated alkadiene telomerization to organo-oxyalkadienes | QUANTUM CHEMICAL CORPORATION (a Virginia corp.) (US) | 1987-04-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10179331-B2 | Ligand based chromium catalyst and application in catalyzing ethylene oligomerization | CHRNE, NOD2, NOD1 | CYP3A4 2033/4885TDP1 1443/4885ALOX15 2800/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.