Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 1/20 | 0.47 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | GUSB | P08236 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 4/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | TYMS | P04818 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28499632 | 0.83 | TNKS (0.46) | TNKS2NPC1TNKSGUSBPARP1 | |
| SCHEMBL14320356 | 0.83 | NPC1 (0.54) | TNKS2NPC1TNKSGUSBPARP1 | |
| SCHEMBL28511274 | 0.74 | PKM (0.50) | NPC1RAB9AEGLN1NPBWR1TYMS | |
| SCHEMBL24996627 | 0.72 | UCHL1 (0.53) | UCHL1SNCANPBWR1MCHR1 | |
| SCHEMBL31357429 | 0.72 | UCHL1 (0.53) | UCHL1SNCANPBWR1MCHR1 | |
| SCHEMBL24997048 | 0.72 | UCHL1 (0.53) | UCHL1SNCANPBWR1MCHR1 | |
| SCHEMBL31510783 | 0.70 | UCHL1 (0.47) | UCHL1SNCANPC1RAB9AADORA2A | |
| SCHEMBL28493868 | 0.70 | TNKS (0.54) | TNKS2NPC1TNKSGUSBPARP1 | |
| SCHEMBL759896 | 0.70 | UCHL1 (0.56) | UCHL1SNCANPBWR1MAPTADORA1 | |
| SCHEMBL4373740 | 0.70 | UCHL1 (0.48) | UCHL1SNCANPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107286169-B | Tankyrase inhibitors | 北京四环制药有限公司 | 2020-11-24 | — | — | CN | disclosed |