Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 17/20 | 0.67 |
| ▸ | WNT3A | P56704 | 13/20 | 0.67 |
| ▸ | TNKS | O95271 | 5/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | LPL | P06858 | 3/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21217938 | 0.84 | WNT3A (0.44) | TNKS2WNT3ATNKSLPLLIPG | |
| SCHEMBL27436974 | 0.81 | TNKS2 (0.62) | TNKS2WNT3ATNKSPARP1LPL | |
| SCHEMBL27438220 | 0.81 | TNKS2 (0.61) | TNKS2WNT3ATNKSPARP1LPL | |
| SCHEMBL28493033 | 0.78 | TNKS2 (1.00) | TNKS2WNT3ATNKSPARP1 | |
| SCHEMBL7783542 | 0.78 | TNKS2 (0.76) | TNKS2WNT3ATNKS | |
| SCHEMBL27440360 | 0.73 | TNKS2 (0.52) | TNKS2WNT3ATNKSPARP1 | |
| SCHEMBL30870702 | 0.73 | TNKS2 (0.52) | TNKS2WNT3ATNKSPARP1 | |
| SCHEMBL27439532 | 0.72 | TNKS2 (0.56) | TNKS2WNT3ATNKSPARP1 | |
| SCHEMBL25320624 | 0.71 | TNKS (0.61) | TNKS2WNT3ATNKSPARP1LPL | |
| SCHEMBL27439660 | 0.70 | TNKS2 (0.48) | TNKS2WNT3ATNKSPARP1LPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107286169-B | Tankyrase inhibitors | 北京四环制药有限公司 | 2020-11-24 | — | — | CN | disclosed |