Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 19/20 | 0.76 |
| ▸ | WNT3A | P56704 | 12/20 | 0.76 |
| ▸ | TNKS | O95271 | 4/20 | 0.56 |
| ▸ | MTHFD2 | P13995 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28493033 | 0.86 | TNKS2 (1.00) | TNKS2WNT3ATNKS | |
| SCHEMBL1033822 | 0.82 | TNKS2 (0.55) | TNKS2WNT3ATNKSMTHFD2 | |
| SCHEMBL1032502 | 0.79 | TNKS2 (0.68) | TNKS2WNT3ATNKSMTHFD2 | |
| SCHEMBL9070566 | 0.79 | TNKS (0.63) | TNKS2WNT3ATNKSMTHFD2 | |
| SCHEMBL28501346 | 0.78 | TNKS2 (0.67) | TNKS2WNT3ATNKS | |
| SCHEMBL14344503 | 0.75 | MTHFD2 (0.49) | TNKS2WNT3ATNKSMTHFD2 | |
| SCHEMBL1035636 | 0.75 | PARP1 (0.53) | TNKS2WNT3ATNKSMTHFD2 | |
| SCHEMBL7783581 | 0.74 | TNKS2 (0.70) | TNKS2WNT3ATNKSMTHFD2 | |
| SCHEMBL7301214 | 0.73 | TNKS2 (0.43) | TNKS2WNT3ATNKS | |
| SCHEMBL1032810 | 0.73 | TNKS2 (0.46) | TNKS2WNT3ATNKSMTHFD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1142881-A1 | POLY(ADP-RIBOSE) POLYMERASE INHIBITORS CONSISTING OF PYRIMIDINE DERIVATIVES | MEIJI SEIKA KAISHA LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |