Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.36 |
| ▸ | DPP4 | P27487 | 8/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 8/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5101181 | 0.84 | — | — | |
| SCHEMBL2385755 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL31340503 | 0.82 | PIM1 (0.33) | — | |
| Trifluoroacetic Acid SCHEMBL28499241 | 0.81 | DPP4 (0.35) | DPP4DPP8DPP7DPP9CHRM3 | |
| SCHEMBL14527947 | 0.78 | MEN1 (0.36) | — | |
| Trifluoroacetic Acid SCHEMBL27171838 | 0.77 | ALDH1A1 (0.41) | IRAK4DPP4DPP8DPP7DPP9 | |
| Trifluoroacetic Acid SCHEMBL27171824 | 0.77 | ALDH1A1 (0.41) | IRAK4DPP4DPP8DPP7DPP9 | |
| Hydrochloric Acid SCHEMBL31340824 | 0.76 | MEN1 (0.35) | — | |
| Trifluoroacetic Acid SCHEMBL28709650 | 0.76 | HSD17B10 (0.39) | DPP4DPP8DPP7DPP9CHRM3 | |
| Trifluoroacetic Acid SCHEMBL29197895 | 0.75 | IRAK4 (0.33) | IRAK4DPP4DPP8DPP7DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111978318-A | Imidazopyridine MNK1/MNK2 kinase inhibitor and preparation method and application thereof | 上海道熵生物科技有限公司 | 2020-11-24 | — | — | CN | disclosed |