SCHEMBL28501608

SCHEMBL28501608

CC(C)(C)c1ccccc1O.CC(C)(N)CN

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.72
TDP1 Q9NUW8 2/20 0.72
TSHR P16473 2/20 0.72
CA2 P00918 3/20 0.45
ALOX15 P16050 4/20 0.41
LMNA P02545 2/20 0.41
HSD17B10 Q99714 2/20 0.41
TYR P14679 2/20 0.41
NR1I2 O75469 1/20 0.41
CYP2C9 P11712 1/20 0.41
MIF P14174 1/20 0.41
HTT P42858 1/20 0.41
NFE2L2 Q16236 1/20 0.41
GABRA1 P14867 1/20 0.39
GABRB2 P47870 1/20 0.39
SMN1; SMN2 Q16637 3/20 0.38
KDM4E B2RXH2 2/20 0.38
MAPT P10636 2/20 0.38
CYP1A2 P05177 1/20 0.38
ATP2A2 P16615 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylenediamine SCHEMBL28248842 0.88 ALDH1A1 (0.78) ALDH1A1TDP1TSHRCA2ALOX15
Methylamine SCHEMBL28181501 0.85 ALDH1A1 (0.90) ALDH1A1TDP1TSHRCA2ALOX15
Methylamine SCHEMBL27543489 0.85 ALDH1A1 (0.90) ALDH1A1TDP1TSHRCA2ALOX15
Hydrazine SCHEMBL29160644 0.85 ALDH1A1 (0.90) ALDH1A1TDP1TSHRCA2ALOX15
SCHEMBL22729938 0.85 ALDH1A1 (1.00) ALDH1A1TDP1TSHRCA2ALOX15
SCHEMBL51803 0.85 ALDH1A1 (1.00) ALDH1A1TDP1TSHRCA2ALOX15
SCHEMBL29358279 0.85 ALDH1A1 (1.00) ALDH1A1TDP1TSHRCA2ALOX15
Propane SCHEMBL2158316 0.83 ALDH1A1 (0.86) ALDH1A1TDP1TSHRCA2ALOX15
SCHEMBL23542116 0.83 ALDH1A1 (0.95) ALDH1A1TDP1TSHRCA2ALOX15
Hydrogen Sulfide SCHEMBL9744629 0.83 ALDH1A1 (0.95) ALDH1A1TDP1TSHRCA2ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111978187-A Synthesis method of dimethyl ethylenediamine tert-butyl phenol 辽宁东野环保产业开发有限公司 2020-11-24 CN disclosed
CN-111978187-A Synthesis method of dimethyl ethylenediamine tert-butyl phenol 辽宁东野环保产业开发有限公司 2020-11-24 CN disclosed
CN-111978187-A Synthesis method of dimethyl ethylenediamine tert-butyl phenol 辽宁东野环保产业开发有限公司 2020-11-24 CN disclosed