Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.38 |
| ▸ | TOP1 | P11387 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28056578 | 0.93 | ESR1 (0.46) | KIF11ESR1TOP1BACE1PDE10A | |
| SCHEMBL28358113 | 0.84 | CYP1A1 (0.45) | AKR1C3AKR1C2ESR1GSTP1HDAC4 | |
| SCHEMBL57186 | 0.84 | GSTP1 (0.52) | AKR1C3AKR1C2ESR1GSTP1HDAC4 | |
| SCHEMBL21223776 | 0.83 | ESR1 (0.40) | KIF11AKR1C3AKR1C2ESR1GSTP1 | |
| SCHEMBL22992968 | 0.82 | ESR1 (0.42) | KIF11AKR1C3AKR1C2ESR1GSTP1 | |
| SCHEMBL22978396 | 0.80 | ESR1 (0.50) | KIF11AKR1C3AKR1C2ESR1GSTP1 | |
| SCHEMBL27525626 | 0.80 | KIF11 (0.47) | KIF11ESR1TOP1BACE1ALDH1A1 | |
| SCHEMBL28086807 | 0.80 | GSTP1 (0.47) | AKR1C3AKR1C2ESR1GSTP1HDAC4 | |
| SCHEMBL28237160 | 0.79 | GPR84 (0.48) | KIF11AKR1C3AKR1C2GPR84HSD17B2 | |
| SCHEMBL27953238 | 0.78 | KIF11 (0.46) | KIF11ESR1TOP1BACE1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112135808-A | Materials for forming nucleation inhibiting coatings and devices incorporating same | OTI照明公司 | 2020-12-25 | — | — | CN | disclosed |