Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAK1 | Q13153 | 15/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | FLT3 | P36888 | 1/20 | 0.49 |
| ▸ | TERT | O14746 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8527905 | 0.77 | PAK1 (0.79) | PAK1MAPK1FLT3TERT | |
| SCHEMBL700484 | 0.75 | PIM1 (0.69) | PAK1MAPK1FLT3 | |
| SCHEMBL700483 | 0.75 | PIM1 (0.69) | PAK1MAPK1FLT3 | |
| SCHEMBL8585959 | 0.75 | PAK1 (0.70) | PAK1MAPK1FLT3 | |
| SCHEMBL8585967 | 0.75 | PAK1 (0.70) | PAK1MAPK1FLT3 | |
| SCHEMBL32682829 | 0.74 | PAK1 (0.66) | PAK1MAPK1TERT | |
| SCHEMBL8415627 | 0.74 | PAK1 (1.00) | PAK1MAPK1FLT3 | |
| SCHEMBL8415630 | 0.74 | PAK1 (1.00) | PAK1MAPK1FLT3 | |
| SCHEMBL8530470 | 0.73 | PAK1 (0.72) | PAK1MAPK1TERT | |
| SCHEMBL31380874 | 0.73 | PAK1 (0.80) | PAK1MAPK1FLT3TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112174943-A | Application of indole-2-ketone compound in preparation of oral bacteria prevention and treatment product | 四川大学 | 2021-01-05 | — | — | CN | disclosed |