SCHEMBL31380874

SCHEMBL31380874

O=C(CCN1CCCCC1)Nc1ccc2c(c1)C(=Cc1cccc3nccn13)C(=O)N2

nearest known ligand 0.80

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ PAK1 Q13153 15/20 0.80
▸ MAPK1 P28482 1/20 0.54
▸ FLT3 P36888 1/20 0.48
▸ TERT O14746 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8530470 0.78 PAK1 (0.72) PAK1MAPK1TERT
SCHEMBL8527905 0.77 PAK1 (0.79) PAK1MAPK1FLT3TERT
Hydrochloric Acid SCHEMBL7554275 0.77 PAK1 (0.77) PAK1MAPK1FLT3
SCHEMBL8585959 0.76 PAK1 (0.70) PAK1MAPK1FLT3
SCHEMBL8585967 0.76 PAK1 (0.70) PAK1MAPK1FLT3
SCHEMBL8415627 0.75 PAK1 (1.00) PAK1MAPK1FLT3
SCHEMBL8415630 0.75 PAK1 (1.00) PAK1MAPK1FLT3
SCHEMBL32682829 0.73 PAK1 (0.66) PAK1MAPK1TERT
SCHEMBL28501759 0.73 PAK1 (0.70) PAK1MAPK1FLT3TERT
SCHEMBL8808140 0.70 PAK1 (0.82) PAK1MAPK1FLT3TERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260070905-A1 Derivatives of Imidazo[1,2-A]Pyridine with Anti-Inflammatory Activity UNIV DE VELENCIA (ES) 2026-03-12 — — US claimed
WO-2025003545-A1 DERIVATIVES OF IMIDAZO[1,2-A]PYRIDINE WITH ANTI-INFLAMMATORY ACTIVITY UNIVERSITAT DE VALÈNCIA (ES) 2025-01-02 — — WO claimed
US-20260070905-A1 Derivatives of Imidazo[1,2-A]Pyridine with Anti-Inflammatory Activity UNIV DE VELENCIA (ES) 2026-03-12 — — US disclosed
WO-2025003545-A1 DERIVATIVES OF IMIDAZO[1,2-A]PYRIDINE WITH ANTI-INFLAMMATORY ACTIVITY UNIVERSITAT DE VALÈNCIA (ES) 2025-01-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260070905-A1 Derivatives of Imidazo[1,2-A]Pyridine with Anti-Inflammatory Activity IL1A, IL6, IL1B PAK1 4173/4885MAPK1 884/4885FLT3 4415/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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