Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.70 |
| ▸ | MEN1 | O00255 | 4/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.70 |
| ▸ | HTT | P42858 | 2/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.70 |
| ▸ | NPC1 | O15118 | 4/20 | 0.66 |
| ▸ | RAB9A | P51151 | 4/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.64 |
| ▸ | CA12 | O43570 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | CA9 | Q16790 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2826334 | 0.96 | KMT2A (0.75) | EPHX1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2827311 | 0.95 | KMT2A (0.72) | EPHX1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2849248 | 0.88 | MEN1 (0.62) | EPHX1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL1206194 | 0.87 | KDM4E (0.72) | EPHX1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2824601 | 0.86 | NPC1 (0.61) | EPHX1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL12196188 | 0.84 | EPHX1 (1.00) | EPHX1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL1204443 | 0.84 | KMT2A (0.69) | EPHX1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL1205663 | 0.83 | KMT2A (0.71) | EPHX1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8059186 | 0.83 | KMT2A (0.55) | KMT2AMEN1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL10192070 | 0.82 | KMT2A (0.82) | EPHX1KDM4EKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2254860-A1 | DERIVATIVES OF 4-(2-AMINO-1-HYDROXYETHYL) PHENOL AS AGONISTS OF THE B2 ADRENERGIC RECEPTOR | Almirall, S.A. (ES) | 2010-12-01 | — | — | EP | disclosed |
| WO-2009106351-A1 | DERIVATIVES OF 4-(2-AMINO-1-HYDROXYETHYL) PHENOL AS AGONISTS OF THE B2 ADRENERGIC RECEPTOR | ALMIRALL, S.A. (ES) | 2009-09-03 | — | — | WO | disclosed |
| EP-2096105-A1 | Derivatives of 4-(2-amino-1-hydroxyethyl)phenol as agonists of the b2 adrenergic receptor | Laboratorios Almirall, S.A. (ES) | 2009-09-02 | — | — | EP | disclosed |