Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GNRHR | P30968 | 2/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ROS1 | P08922 | 1/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.36 |
| ▸ | C5 | P01031 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30870613 | 1.00 | POLB (0.40) | POLBALOX15MAPTALDH1A1GNRHR | |
| SCHEMBL28508892 | 0.89 | POLB (0.40) | POLBMAPTALDH1A1MTNR1AMTNR1B | |
| SCHEMBL30870543 | 0.89 | POLB (0.40) | POLBMAPTALDH1A1MTNR1AMTNR1B | |
| SCHEMBL28507962 | 0.88 | POLB (0.39) | POLBMAPTALDH1A1MTNR1AMTNR1B | |
| SCHEMBL30870585 | 0.88 | POLB (0.39) | POLBMAPTALDH1A1MTNR1AMTNR1B | |
| SCHEMBL28498691 | 0.87 | POLB (0.46) | POLBMAPTALDH1A1LMNAHTT | |
| SCHEMBL30870537 | 0.87 | POLB (0.46) | POLBMAPTALDH1A1LMNAHTT | |
| SCHEMBL28502106 | 0.83 | POLB (0.45) | POLBMAPTALDH1A1MTNR1AMTNR1B | |
| SCHEMBL30870626 | 0.83 | POLB (0.45) | POLBMAPTALDH1A1MTNR1AMTNR1B | |
| SCHEMBL30870533 | 0.83 | POLB (0.44) | POLBMAPTALDH1A1MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112074511-B | Substituted benzodiazoles and their use in therapy | 托马斯·黑勒戴药物研究基金会 | 2024-04-26 | — | — | CN | disclosed |
| CN-112074511-A | Substituted benzodiazoles and their use in therapy | 托马斯·黑勒戴药物研究基金会 | 2020-12-11 | — | — | CN | disclosed |