Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30870537 | 1.00 | POLB (0.46) | POLBGRM4SMN1; SMN2KMT2ANPC1 | |
| SCHEMBL30870613 | 0.87 | POLB (0.40) | POLBGRM4KMT2AMAPTAPOBEC3G | |
| SCHEMBL28502104 | 0.87 | POLB (0.40) | POLBGRM4KMT2AMAPTAPOBEC3G | |
| SCHEMBL30870543 | 0.87 | POLB (0.40) | POLBGRM4KMT2AMEN1MAPT | |
| SCHEMBL28508892 | 0.87 | POLB (0.40) | POLBGRM4KMT2AMEN1MAPT | |
| SCHEMBL28507962 | 0.86 | POLB (0.39) | POLBGRM4KMT2AMEN1MAPT | |
| SCHEMBL30870585 | 0.86 | POLB (0.39) | POLBGRM4KMT2AMEN1MAPT | |
| SCHEMBL28506837 | 0.85 | ADRB2 (0.37) | POLBSMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL30870626 | 0.82 | POLB (0.45) | POLBGRM4SMN1; SMN2KMT2ANPC1 | |
| SCHEMBL28502106 | 0.82 | POLB (0.45) | POLBGRM4SMN1; SMN2KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112074511-B | Substituted benzodiazoles and their use in therapy | 托马斯·黑勒戴药物研究基金会 | 2024-04-26 | — | — | CN | disclosed |
| CN-112074511-A | Substituted benzodiazoles and their use in therapy | 托马斯·黑勒戴药物研究基金会 | 2020-12-11 | — | — | CN | disclosed |