Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28504220 | 0.90 | ALDH1A1 (0.33) | LMNAALDH1A1TDP1L3MBTL1MAPT | |
| SCHEMBL28494644 | 0.80 | IDO1 (0.34) | PDCD1CD274DPP4TSHR | |
| SCHEMBL28506920 | 0.76 | SMN1; SMN2 (0.37) | LMNA | |
| SCHEMBL28494588 | 0.76 | IDO1 (0.32) | — | |
| SCHEMBL28496027 | 0.74 | PDE4B (0.30) | — | |
| SCHEMBL28500239 | 0.73 | SMN1; SMN2 (0.35) | LMNA | |
| SCHEMBL28503065 | 0.72 | PDCD1 (0.39) | LMNAALDH1A1TDP1L3MBTL1CYP1A2 | |
| SCHEMBL28502205 | 0.71 | HTR2A (0.43) | ALDH1A1CYP1A2CYP2C9CYP2C19DPP4 | |
| SCHEMBL28346276 | 0.66 | MAOA (0.37) | ALDH1A1TDP1L3MBTL1KMT2APOLB | |
| SCHEMBL776889 | 0.64 | DPP4 (0.58) | LMNAALDH1A1TDP1L3MBTL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111620914-B | Side-arm metallocene tetravalent transition metal complex containing neutral benzyl heteroatom ligand and application thereof | 吉林大学 | 2021-03-19 | — | — | CN | disclosed |
| CN-111620914-A | Side-arm metallocene tetravalent transition metal complex containing neutral benzyl heteroatom ligand and application thereof | 吉林大学 | 2020-09-04 | — | — | CN | disclosed |