Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUCY1A1 | Q02108 | 19/20 | 0.56 |
| ▸ | GUCY1B1 | Q02153 | 19/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28507109 | 0.93 | GUCY1A1 (0.49) | GUCY1A1GUCY1B1ADORA3KCNH2 | |
| SCHEMBL23162036 | 0.89 | GUCY1A1 (0.56) | GUCY1A1GUCY1B1ADORA3KCNH2 | |
| SCHEMBL28507122 | 0.85 | ADORA3 (0.48) | GUCY1A1GUCY1B1ADORA3KCNH2 | |
| SCHEMBL23161933 | 0.85 | GUCY1A1 (0.59) | GUCY1A1GUCY1B1 | |
| SCHEMBL30937506 | 0.83 | ADORA3 (0.50) | GUCY1A1GUCY1B1ADORA3KCNH2 | |
| SCHEMBL23161959 | 0.83 | ADORA3 (0.50) | GUCY1A1GUCY1B1ADORA3KCNH2 | |
| SCHEMBL23161967 | 0.83 | GUCY1A1 (0.58) | GUCY1A1GUCY1B1 | |
| SCHEMBL23186734 | 0.83 | GUCY1A1 (0.56) | GUCY1A1GUCY1B1ADORA3KCNH2 | |
| SCHEMBL28496288 | 0.83 | GUCY1A1 (0.42) | GUCY1A1GUCY1B1 | |
| SCHEMBL23162035 | 0.81 | GUCY1A1 (0.59) | GUCY1A1GUCY1B1ADORA3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108727340-B | Fluorine substituted indazoles and use thereof | 广东东阳光药业有限公司 | 2020-12-29 | — | — | CN | disclosed |