Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | GUCY1A1 | Q02108 | 14/20 | 0.45 |
| ▸ | GUCY1B1 | Q02153 | 14/20 | 0.45 |
| ▸ | PDE5A | O76074 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | BUB1 | O43683 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23161959 | 1.00 | ADORA3 (0.50) | ADORA3KCNH2GUCY1A1GUCY1B1PDE5A | |
| SCHEMBL28500468 | 0.90 | ADORA3 (0.43) | ADORA3KCNH2GUCY1A1GUCY1B1PDE5A | |
| SCHEMBL28507122 | 0.89 | ADORA3 (0.48) | ADORA3KCNH2GUCY1A1GUCY1B1PDE5A | |
| SCHEMBL20534384 | 0.89 | ADORA3 (0.51) | ADORA3KCNH2GUCY1A1GUCY1B1PDE5A | |
| SCHEMBL20534383 | 0.88 | ADORA3 (0.49) | ADORA3KCNH2GUCY1A1GUCY1B1PDE5A | |
| SCHEMBL28495776 | 0.87 | ADORA3 (0.44) | ADORA3KCNH2GUCY1A1GUCY1B1PDE5A | |
| SCHEMBL23161922 | 0.86 | ADORA3 (0.39) | ADORA3KCNH2GUCY1A1GUCY1B1PDE5A | |
| SCHEMBL23161966 | 0.85 | ADORA3 (0.51) | ADORA3KCNH2GUCY1A1GUCY1B1PDE5A | |
| SCHEMBL29637237 | 0.85 | ADORA3 (0.51) | ADORA3KCNH2GUCY1A1GUCY1B1PDE5A | |
| SCHEMBL28503537 | 0.85 | KCNK13 (0.39) | ADORA3KCNH2GUCY1A1GUCY1B1PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118221651-A | Crystal forms of fluorine substituted indazole compound and use thereof | 广东东阳光药业股份有限公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-118221649-A | Crystal forms of fluorine substituted indazole compound and use thereof | 广东东阳光药业股份有限公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-118221650-A | Crystal forms of fluorine substituted indazole compound and use thereof | 广东东阳光药业股份有限公司 | 2024-06-21 | — | — | CN | disclosed |