Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.71 |
| ▸ | DRD2 | P14416 | 1/20 | 0.69 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.69 |
| ▸ | HTR2A | P28223 | 10/20 | 0.67 |
| ▸ | DRD3 | P35462 | 10/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3249919 | 0.89 | ACHE (0.71) | ACHEDRD2SLC6A4HTR2ADRD3 | |
| SCHEMBL604085 | 0.89 | ACHE (0.71) | ACHEDRD2SLC6A4HTR2ADRD3 | |
| SCHEMBL1545611 | 0.86 | ACHE (0.93) | ACHEDRD2SLC6A4HTR2ADRD3 | |
| SCHEMBL604059 | 0.85 | HTR2A (0.73) | ACHEDRD2SLC6A4HTR2ADRD3 | |
| SCHEMBL604841 | 0.85 | HTR2A (0.73) | ACHEDRD2SLC6A4HTR2ADRD3 | |
| SCHEMBL606612 | 0.85 | HTR2A (0.73) | ACHEDRD2SLC6A4HTR2ADRD3 | |
| SCHEMBL3240892 | 0.85 | HTR2A (0.73) | ACHEDRD2SLC6A4HTR2ADRD3 | |
| SCHEMBL9532457 | 0.84 | ACHE (0.77) | ACHEDRD2SLC6A4HTR2ADRD3 | |
| SCHEMBL7722977 | 0.84 | ACHE (0.80) | ACHEDRD2SLC6A4HTR2ADRD3 | |
| SCHEMBL793025 | 0.84 | ACHE (0.80) | ACHEDRD2SLC6A4HTR2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107793408-B | Piperidine amino derivatives and their use for the treatment of schizophrenia | 上海医药工业研究院 | 2020-12-08 | — | — | CN | disclosed |