SCHEMBL3385183

SCHEMBL3385183

CC[n+]1ccccc1C=Cc1ccc(N(C)C)cc1

nearest known ligand 0.97

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 9/20 0.97
KMT2A Q03164 9/20 0.97
RAB9A P51151 7/20 0.97
NPC1 O15118 5/20 0.97
HTT P42858 5/20 0.97
MAPT P10636 5/20 0.97
ALDH1A1 P00352 4/20 0.97
SMN1; SMN2 Q16637 4/20 0.97
STAT3 P40763 1/20 0.97
KDM4A O75164 4/20 0.71
KDM2A Q9Y2K7 4/20 0.71
APOBEC3A P31941 2/20 0.67
APOBEC3G Q9HC16 2/20 0.67
GFER P55789 2/20 0.67
LMNA P02545 4/20 0.56
NPSR1 Q6W5P4 4/20 0.56
POLB P06746 3/20 0.56
THRB P10828 3/20 0.56
PPARG P37231 2/20 0.56
NCOA2 Q15596 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3870022 1.00 MEN1 (0.97) MEN1KMT2ARAB9ANPC1HTT
Iodide SCHEMBL285058 0.98 MEN1 (1.00) MEN1KMT2ARAB9ANPC1HTT
Iodide SCHEMBL29837406 0.98 MEN1 (1.00) MEN1KMT2ARAB9ANPC1HTT
Iodide SCHEMBL285057 0.98 MEN1 (1.00) MEN1KMT2ARAB9ANPC1HTT
SCHEMBL140215 0.91 KMT2A (0.82) MEN1KMT2ARAB9ANPC1HTT
SCHEMBL29681553 0.91 KMT2A (0.82) MEN1KMT2ARAB9ANPC1HTT
SCHEMBL140214 0.91 KMT2A (0.82) MEN1KMT2ARAB9ANPC1HTT
SCHEMBL21005773 0.88 KDM4A (0.81) MEN1KMT2ARAB9ANPC1HTT
SCHEMBL6530337 0.87 MEN1 (0.74) MEN1KMT2ARAB9ANPC1HTT
Perchlorate SCHEMBL1405638 0.86 KMT2A (0.74) MEN1KMT2ARAB9ANPC1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117467432-A Spherical host-guest type metal organic hybrid material for monochromatic multimode laser output and preparation method thereof 浙江大学 2024-01-30 CN claimed
EP-1200051-B1 AGENT FOR DYING KERATIN FIBERS HENKEL KGAA (DE) 2006-02-01 EP claimed
US-20050048000-A1 Amyloid targeting imaging agents and uses thereof NEUROCHEM (INTERNATIONAL) LIMITED (CH) 2005-03-03 US claimed
EP-1303311-A2 AMYLOID TARGETING IMAGING AGENTS AND USES THEREOF Neurochem, Inc. (CA) 2003-04-23 EP claimed
US-20020115717-A1 Amyloid targeting imaging agents and uses thereof NEUROCHEM (INTERNATIONAL) LIMITED (GI) 2002-08-22 US claimed
WO-2002007781-A2 AMYLOID TARGETING IMAGING AGENTS AND USES THEREOF NEUROCHEM INC. (CA) 2002-01-31 WO claimed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
EP-0615855-B1 Recording sheets containing pyridinium and/or piperazinum compounds XEROX CORP (US) 1997-05-14 EP claimed
EP-0527186-A4 UNIV ILLINOIS (US) 1995-01-18 EP claimed
EP-0527186-A1 PHOTODYNAMIC PLANT DEFOLIANTS AND CHLOROPHYLL BIOSYNTHESIS MODULATORS The Board of Trustees for the University of Illinois (US) 1993-02-17 EP claimed
WO-1991016820-A1 PHOTODYNAMIC PLANT DEFOLIANTS AND CHLOROPHYLL BIOSYNTHESIS MODULATORS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 1991-11-14 WO claimed
CN-117467432-A Spherical host-guest type metal organic hybrid material for monochromatic multimode laser output and preparation method thereof 浙江大学 2024-01-30 CN disclosed
US-9918989-B2 Combination therapies for malaria THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2018-03-20 US disclosed
US-20160151379-A1 COMBINATION THERAPIES FOR MALARIA THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2016-06-02 US disclosed
EP-1432390-B2 DYEING COMPOSITION WITH A BRIGHTENING EFFECT FOR HAIR ORÉAL L (FR) 2015-04-15 EP disclosed
EP-0527186-A4 UNIV ILLINOIS (US) 1995-01-18 EP disclosed
US-5242892-A With 5-aminolevulinic acid THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 1993-09-07 US disclosed
EP-0527186-A1 PHOTODYNAMIC PLANT DEFOLIANTS AND CHLOROPHYLL BIOSYNTHESIS MODULATORS The Board of Trustees for the University of Illinois (US) 1993-02-17 EP disclosed
WO-1991016820-A1 PHOTODYNAMIC PLANT DEFOLIANTS AND CHLOROPHYLL BIOSYNTHESIS MODULATORS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 1991-11-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050048000-A1 Amyloid targeting imaging agents and uses thereof APP, APBA1, BACE1 MEN1 605/4885KMT2A 3512/4885RAB9A 2683/4885
US-20020115717-A1 Amyloid targeting imaging agents and uses thereof APP, APBA1, BACE1 MEN1 605/4885KMT2A 3512/4885RAB9A 2683/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.