SCHEMBL140214

SCHEMBL140214

CC[n+]1ccccc1/C=C/C=C/c1ccc(N(C)C)cc1

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 9/20 0.82
RAB9A P51151 8/20 0.82
MEN1 O00255 8/20 0.82
MAPT P10636 7/20 0.82
HTT P42858 6/20 0.82
NPC1 O15118 5/20 0.82
ALDH1A1 P00352 4/20 0.82
SMN1; SMN2 Q16637 3/20 0.82
STAT3 P40763 1/20 0.82
KDM4A O75164 4/20 0.61
KDM2A Q9Y2K7 4/20 0.61
APOBEC3A P31941 2/20 0.57
APOBEC3G Q9HC16 2/20 0.57
GFER P55789 2/20 0.57
APP P05067 2/20 0.53
NPSR1 Q6W5P4 5/20 0.51
L3MBTL1 Q9Y468 4/20 0.51
THRB P10828 3/20 0.51
LMNA P02545 3/20 0.51
NSD2 O96028 3/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29681553 1.00 KMT2A (0.82) KMT2ARAB9AMEN1MAPTHTT
SCHEMBL140215 1.00 KMT2A (0.82) KMT2ARAB9AMEN1MAPTHTT
Perchlorate SCHEMBL29391475 0.95 KMT2A (0.74) KMT2ARAB9AMEN1MAPTHTT
Perchlorate SCHEMBL1405638 0.95 KMT2A (0.74) KMT2ARAB9AMEN1MAPTHTT
Perchlorate SCHEMBL1337764 0.95 KMT2A (0.74) KMT2ARAB9AMEN1MAPTHTT
SCHEMBL3870022 0.91 MEN1 (0.97) KMT2ARAB9AMEN1MAPTHTT
SCHEMBL3385183 0.91 MEN1 (0.97) KMT2ARAB9AMEN1MAPTHTT
Iodide SCHEMBL285058 0.90 MEN1 (1.00) KMT2ARAB9AMEN1MAPTHTT
Iodide SCHEMBL285057 0.90 MEN1 (1.00) KMT2ARAB9AMEN1MAPTHTT
Iodide SCHEMBL29837406 0.90 MEN1 (1.00) KMT2ARAB9AMEN1MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210165132-A1 FLEXIBLE DISPLAY COVER SUBSTRATE MICROCOSM TECHNOLOGY CO., LTD. (TW) 2021-06-03 US claimed
US-20230167303-A1 COLOR MATCHED AND BRIGHT FLUORESCENT MATERIALS COMPOSED OF SMALL-MOLECULE IONIC LATTICES UNIVERSITY OF COPENHAGEN (DK) 2023-06-01 US disclosed
US-20210165132-A1 FLEXIBLE DISPLAY COVER SUBSTRATE MICROCOSM TECHNOLOGY CO., LTD. (TW) 2021-06-03 US disclosed
US-20200407628-A1 COLOR MATCHED AND BRIGHT FLUORESCENT MATERIALS COMPOSED OF SMALL-MOLECULE IONIC LATTICES UNIVERSITY OF COPENHAGEN (DK) 2020-12-31 US disclosed
US-8906354-B2 Loaded latex optical molecular imaging probes containing lipophilic large stokes shift dyes BRUKER BIOSPIN CORPORATION (US) 2014-12-09 US disclosed
US-8841134-B2 Fluorescence resonance energy transfer detection with nanoparticles for in vitro and in vivo applications BRUKER BIOSPIN CORPORATION (US) 2014-09-23 US disclosed
US-8362447-B2 Degradable taggant and method of making and using thereof WORCESTER POLYTECHNIC INSTITUTE (US) 2013-01-29 US disclosed
US-20120058050-A1 LOADED LATEX OPTICAL MOLECULAR IMAGING PROBES CONTAINING LIPOPHILIC LARGE STOKES SHIFT DYES BRUKER BIOSPIN CORPORATION 2012-03-08 US disclosed
US-20120035187-A1 ANTI-NEURODEGENERATIVE DISEASE AGENT KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 2012-02-09 US disclosed
US-20100288943-A1 DEGRADABLE TAGGANT AND METHOD OF MAKING AND USING THEREOF WORCESTER POLYTECHNIC INSTITUTE (US) 2010-11-18 US disclosed
US-20100034748-A1 Molecular imaging probes based on loaded reactive nano-scale latex QUANTUM MEDICAL HOLDINGS, LLC 2010-02-11 US disclosed
US-20090061532-A1 FLUORESCENCE RESONANCE ENERGY TRANSFER DETECTION WITH NANOPARTICLES FOR IN VITRO AND IN VIVO APPLICATIONS CARESTREAM HEALTH, INC. 2009-03-05 US disclosed
US-20080181965-A1 Loaded latex optical molecular imaging probes QUANTUM MEDICAL HOLDINGS, LLC 2008-07-31 US disclosed
US-20070152571-A1 ORGANIC EL PANEL FUJI ELECTRIC HOLDINGS CO., LTD (JP) 2007-07-05 US disclosed
US-6667830-B1 Super-resolution microscope system and method for illumination JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2003-12-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080181965-A1 Loaded latex optical molecular imaging probes MLX, LOXL1, EPX KMT2A 2878/4885RAB9A 4669/4885MEN1 3048/4885
US-20100034748-A1 Molecular imaging probes based on loaded reactive nano-scale latex CLTA, COPE, CD68 KMT2A 2753/4885RAB9A 4122/4885MEN1 2615/4885
US-20120035187-A1 ANTI-NEURODEGENERATIVE DISEASE AGENT SNCA, PSEN1, CDR2 KMT2A 2624/4885RAB9A 1423/4885MEN1 2218/4885
US-20120058050-A1 LOADED LATEX OPTICAL MOLECULAR IMAGING PROBES CONTAINING LIPOPHILIC LARGE STOKES SHIFT DYES LASP1, LSS, SELL KMT2A 3321/4885RAB9A 1834/4885MEN1 2790/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.