Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 19/20 | 0.49 |
| ▸ | MTHFD1 | P11586 | 1/20 | 0.41 |
| ▸ | MTHFD2 | P13995 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28505981 | 1.00 | FPR2 (0.49) | FPR2MTHFD1MTHFD2MEN1NPC1 | |
| SCHEMBL21494610 | 0.80 | FPR2 (0.68) | FPR2MTHFD1MTHFD2 | |
| SCHEMBL21494747 | 0.79 | FPR2 (0.67) | FPR2MTHFD1MTHFD2 | |
| SCHEMBL21494742 | 0.77 | FPR2 (0.71) | FPR2MTHFD1MTHFD2 | |
| SCHEMBL21494644 | 0.75 | FPR2 (0.69) | FPR2MTHFD1MTHFD2 | |
| SCHEMBL21494613 | 0.72 | FPR2 (0.72) | FPR2MTHFD1MTHFD2 | |
| SCHEMBL30945386 | 0.71 | FPR2 (0.64) | FPR2MTHFD1MTHFD2 | |
| SCHEMBL29231716 | 0.71 | FPR2 (0.64) | FPR2MTHFD1MTHFD2 | |
| SCHEMBL14659730 | 0.69 | NPSR1 (0.41) | — | |
| SCHEMBL21515026 | 0.66 | FPR2 (0.66) | FPR2MTHFD1MTHFD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112218858-A | 2, 6-diamino-3, 4-dihydropyrimidin-4-one derivatives and their use in therapy | 托马斯·黑勒戴药物研究基金会 | 2021-01-12 | — | — | CN | disclosed |