Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 16/20 | 0.64 |
| ▸ | MTHFD1 | P11586 | 1/20 | 0.60 |
| ▸ | MTHFD2 | P13995 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.39 |
| ▸ | GART | P22102 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29231716 | 1.00 | FPR2 (0.64) | FPR2MTHFD1MTHFD2HIF1AGART | |
| SCHEMBL21494644 | 0.95 | FPR2 (0.69) | FPR2MTHFD1MTHFD2GART | |
| SCHEMBL21494747 | 0.92 | FPR2 (0.67) | FPR2MTHFD1MTHFD2GART | |
| SCHEMBL21494613 | 0.85 | FPR2 (0.72) | FPR2MTHFD1MTHFD2GART | |
| SCHEMBL21494662 | 0.81 | MEN1 (0.51) | HIF1A | |
| SCHEMBL25745634 | 0.79 | FPR2 (0.72) | FPR2MTHFD1MTHFD2GART | |
| SCHEMBL29231831 | 0.78 | FPR2 (0.63) | FPR2MTHFD1MTHFD2GART | |
| SCHEMBL30106791 | 0.78 | FPR2 (1.00) | FPR2MTHFD1MTHFD2 | |
| SCHEMBL21494722 | 0.78 | FPR2 (1.00) | FPR2MTHFD1MTHFD2 | |
| SCHEMBL21494720 | 0.78 | FPR2 (1.00) | FPR2MTHFD1MTHFD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112218858-B | 2, 6-Diamino-3, 4-dihydropyrimidin-4-one derivatives and their use in therapy | 托马斯·黑勒戴药物研究基金会 | 2024-06-18 | — | — | CN | disclosed |