Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.30 |
| ▸ | TTR | P02766 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28512384 | 0.84 | AOC3 (0.34) | GAAAOC3 | |
| SCHEMBL28505879 | 0.83 | OPRM1 (0.33) | OPRM1OPRD1OPRK1ABCG2 | |
| SCHEMBL28504576 | 0.82 | GAA (0.34) | GAAAOC3 | |
| SCHEMBL21107304 | 0.81 | CA12 (0.38) | OPRM1OPRD1OPRK1 | |
| SCHEMBL29612684 | 0.81 | CA12 (0.38) | OPRM1OPRD1OPRK1 | |
| SCHEMBL28993860 | 0.78 | TTR (0.32) | TTR | |
| SCHEMBL21069517 | 0.78 | CRBN (0.36) | OPRM1OPRD1OPRK1ABCG2TTR | |
| SCHEMBL25957714 | 0.78 | MGMT (0.32) | OPRM1OPRD1OPRK1ABCG2 | |
| SCHEMBL21070193 | 0.75 | MGMT (0.33) | OPRM1OPRD1OPRK1ABCG2 | |
| SCHEMBL20585898 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112105385-A | IRAK degrading agents and uses thereof | 凯麦拉医疗公司 | 2020-12-18 | — | — | CN | disclosed |