Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 5/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28504576 | 0.87 | GAA (0.34) | AOC3GAAALDH1A1LMNANPC1 | |
| SCHEMBL28506992 | 0.84 | OPRM1 (0.34) | AOC3GAA | |
| SCHEMBL21069508 | 0.82 | LMNA (0.37) | LMNA | |
| SCHEMBL29612726 | 0.79 | CA1 (0.43) | — | |
| SCHEMBL21107305 | 0.79 | CA1 (0.43) | — | |
| SCHEMBL29104752 | 0.75 | ACHE (0.32) | ALDH1A1 | |
| SCHEMBL28656034 | 0.75 | ACHE (0.32) | ALDH1A1 | |
| SCHEMBL27972821 | 0.75 | ACHE (0.32) | ALDH1A1 | |
| SCHEMBL31425438 | 0.75 | ACHE (0.32) | ALDH1A1 | |
| SCHEMBL21071061 | 0.75 | SMN1; SMN2 (0.39) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112105385-A | IRAK degrading agents and uses thereof | 凯麦拉医疗公司 | 2020-12-18 | — | — | CN | disclosed |