Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 8/20 | 0.49 |
| ▸ | FAAH | O00519 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.49 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30600492 | 0.79 | MGLL (0.59) | MGLLFAAHALDH1A1HPGDHSP90AA1 | |
| SCHEMBL29066046 | 0.79 | MGLL (0.59) | MGLLFAAHALDH1A1HPGDHSP90AA1 | |
| SCHEMBL5345848 | 0.78 | MGLL (0.63) | MGLLFAAHALDH1A1HPGDHSP90AA1 | |
| SCHEMBL18891500 | 0.78 | PTGS1 (0.58) | MGLLFAAHALDH1A1HPGDHSP90AA1 | |
| SCHEMBL8097410 | 0.77 | MGLL (0.57) | MGLLFAAHALDH1A1HPGDHSP90AA1 | |
| SCHEMBL5361313 | 0.76 | MGLL (0.61) | MGLLFAAHALDH1A1HPGDHSP90AA1 | |
| SCHEMBL17367597 | 0.75 | MGLL (0.47) | MGLLFAAHALDH1A1HPGDHSP90AA1 | |
| SCHEMBL27962820 | 0.75 | DUT (0.36) | EPHX1 | |
| SCHEMBL21632664 | 0.75 | MGLL (0.59) | MGLLFAAHALDH1A1HPGDHSP90AA1 | |
| SCHEMBL21348323 | 0.75 | MGLL (0.59) | MGLLFAAHALDH1A1HPGDHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107141348-B | Long-acting exenatide (Exendin-4) analogue and application thereof | 中国药科大学 | 2021-01-15 | — | — | CN | disclosed |