⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4384324 | 0.74 | — | — | |
| SCHEMBL1521980 | 0.71 | — | — | |
| SCHEMBL14566745 | 0.71 | — | — | |
| SCHEMBL28407315 | 0.69 | — | — | |
| SCHEMBL5943470 | 0.67 | — | — | |
| SCHEMBL28542583 | 0.67 | MAOA (0.35) | — | |
| SCHEMBL28395579 | 0.67 | TSHR (0.45) | — | |
| SCHEMBL45244 | 0.65 | TSHR (0.71) | — | |
| SCHEMBL820078 | 0.65 | — | — | |
| Ethylene SCHEMBL2496871 | 0.65 | TSHR (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117924305-B | Chiral benzooctone compound and synthetic method and application thereof | 济南市中心医院 | 2025-02-28 | — | — | CN | claimed |
| CN-117924305-A | Chiral benzooctone compound and synthetic method and application thereof | 济南市中心医院 | 2024-04-26 | — | — | CN | claimed |
| CN-115043850-B | Method for synthesizing chiral oxygen-containing octatomic ring compound through palladium-catalyzed asymmetric allyl cycloaddition reaction | 山东大学 | 2024-02-02 | — | — | CN | claimed |
| CN-116854656-A | Synthesis method of polysubstituted 3,4,5, 6-tetrahydro-2H-oxacyclooctatriene compound | 青岛科技大学 | 2023-10-10 | — | — | CN | claimed |
| CN-115043850-A | Method for synthesizing chiral oxygen-containing eight-membered ring compound through palladium-catalyzed asymmetric allylic cycloaddition reaction | 山东大学 | 2022-09-13 | — | — | CN | claimed |
| CN-112940002-B | Method for synthesizing octatomic bridged ring compound through palladium-catalyzed asymmetric ring addition reaction | 山东大学 | 2022-07-15 | — | — | CN | claimed |
| CN-114426511-A | Method for preparing chiral spiro [2.4] heptane compounds through palladium-catalyzed asymmetric cycloaddition reaction | 山东大学 | 2022-05-03 | — | — | CN | claimed |
| CN-113583015-A | Method for synthesizing chiral oxygen-containing eight-membered ring compound through palladium-catalyzed asymmetric allylic cycloaddition reaction | 山东大学 | 2021-11-02 | — | — | CN | claimed |
| CN-112940002-A | Method for synthesizing eight-membered bridged ring compound through palladium-catalyzed asymmetric ring addition reaction | 山东大学 | 2021-06-11 | — | — | CN | claimed |
| CN-117924305-B | Chiral benzooctone compound and synthetic method and application thereof | 济南市中心医院 | 2025-02-28 | — | — | CN | disclosed |
| CN-117924305-B | Chiral benzooctone compound and synthetic method and application thereof | 济南市中心医院 | 2025-02-28 | — | — | CN | disclosed |
| CN-117924305-A | Chiral benzooctone compound and synthetic method and application thereof | 济南市中心医院 | 2024-04-26 | — | — | CN | disclosed |
| CN-117924305-A | Chiral benzooctone compound and synthetic method and application thereof | 济南市中心医院 | 2024-04-26 | — | — | CN | disclosed |
| CN-117645611-A | Method for synthesizing chiral octacyclic ether compound | 山东大学苏州研究院 | 2024-03-05 | — | — | CN | disclosed |
| CN-114426511-A | Method for preparing chiral spiro [2.4] heptane compounds through palladium-catalyzed asymmetric cycloaddition reaction | 山东大学 | 2022-05-03 | — | — | CN | disclosed |
| CN-113583015-A | Method for synthesizing chiral oxygen-containing eight-membered ring compound through palladium-catalyzed asymmetric allylic cycloaddition reaction | 山东大学 | 2021-11-02 | — | — | CN | disclosed |
| CN-113583015-A | Method for synthesizing chiral oxygen-containing eight-membered ring compound through palladium-catalyzed asymmetric allylic cycloaddition reaction | 山东大学 | 2021-11-02 | — | — | CN | disclosed |
| CN-112940002-A | Method for synthesizing eight-membered bridged ring compound through palladium-catalyzed asymmetric ring addition reaction | 山东大学 | 2021-06-11 | — | — | CN | disclosed |
| CN-112940002-A | Method for synthesizing eight-membered bridged ring compound through palladium-catalyzed asymmetric ring addition reaction | 山东大学 | 2021-06-11 | — | — | CN | disclosed |
| CN-107383251-B | Catalyst system for catalyzing polymerization of polar conjugated olefin | 苏州大学 | 2021-01-29 | — | — | CN | disclosed |