Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.50 |
| ▸ | MST1R | Q04912 | 1/20 | 0.50 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.49 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.49 |
| ▸ | CCNC | P24863 | 2/20 | 0.46 |
| ▸ | CDK8 | P49336 | 2/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.42 |
| ▸ | CLK1 | P49759 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.41 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.41 |
| ▸ | WNT1 | P04628 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15729483 | 0.80 | PRMT5 (0.49) | MKNK1MKNK2CCNCCDK8MAP4K4 | |
| SCHEMBL21753343 | 0.80 | MAPT (0.44) | MKNK1MKNK2CCNCCDK8MAP4K4 | |
| Hydrochloric Acid SCHEMBL17091012 | 0.79 | PRMT5 (0.48) | METMKNK1MKNK2CCNCCDK8 | |
| Hydrochloric Acid SCHEMBL17090879 | 0.79 | PRMT5 (0.48) | METMKNK1MKNK2CCNCCDK8 | |
| SCHEMBL17212043 | 0.79 | MAPT (0.45) | MKNK1MKNK2IRAK4CLK1KCNH2 | |
| SCHEMBL17091406 | 0.78 | CLK1 (0.47) | METMAP4K4CLK1EP300 | |
| SCHEMBL21769966 | 0.77 | MAPT (0.44) | MKNK1MKNK2IRAK4CLK1KCNH2 | |
| SCHEMBL2714933 | 0.77 | GABRA1 (0.42) | MKNK1MKNK2CYP11B2KCNH2ATM | |
| SCHEMBL31289903 | 0.76 | SRC (0.59) | METMST1RCLK1WNT1GSK3B | |
| SCHEMBL17675497 | 0.76 | CYP1A2 (0.43) | CYP11B2KCNH2ABL1LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112218857-B | P300/CBP HAT inhibitors and methods of use thereof | 星座制药公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-114450005-A | Compounds for the treatment of neurological disorders | 星座制药公司 | 2022-05-06 | — | — | CN | disclosed |
| CN-112218857-A | P300/CBP HAT inhibitors and methods of use thereof | 星座制药公司 | 2021-01-12 | — | — | CN | disclosed |