Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2878426 | 0.85 | ALDH1A1 (0.52) | ALDH1A1HPGDALOX15MGLLHSD17B10 | |
| SCHEMBL6492027 | 0.80 | ALDH1A1 (0.55) | ALDH1A1HPGDALOX15HSD17B10MEN1 | |
| SCHEMBL1063179 | 0.79 | ALDH1A1 (0.67) | ALDH1A1HPGDALOX15MGLLHSD17B10 | |
| SCHEMBL14155927 | 0.76 | ALDH1A1 (0.55) | ALDH1A1HPGDALOX15MGLLHSD17B10 | |
| SCHEMBL4833816 | 0.76 | ALDH1A1 (0.55) | ALDH1A1HPGDALOX15MGLLHSD17B10 | |
| SCHEMBL27634785 | 0.76 | ALDH1A1 (0.51) | ALDH1A1HPGDALOX15MGLLHSD17B10 | |
| SCHEMBL27512046 | 0.76 | ALDH1A1 (0.51) | ALDH1A1HPGDALOX15MGLLHSD17B10 | |
| SCHEMBL27624516 | 0.76 | ALDH1A1 (0.51) | ALDH1A1HPGDALOX15MGLLHSD17B10 | |
| SCHEMBL4410499 | 0.75 | ALDH1A1 (0.54) | ALDH1A1HPGDALOX15MGLLHSD17B10 | |
| SCHEMBL4409961 | 0.75 | ALDH1A1 (0.54) | ALDH1A1HPGDALOX15MGLLHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112041301-A | Compounds having iron death inducing activity and methods of use thereof | 费罗治疗公司 | 2020-12-04 | — | — | CN | disclosed |