Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Cyclohexanol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | MMP2 | P08253 | 8/20 | 0.41 |
| ▸ | CA12 | O43570 | 6/20 | 0.41 |
| ▸ | CA1 | P00915 | 6/20 | 0.41 |
| ▸ | CA2 | P00918 | 6/20 | 0.41 |
| ▸ | CA9 | Q16790 | 6/20 | 0.41 |
| ▸ | MMP1 | P03956 | 3/20 | 0.41 |
| ▸ | MMP8 | P22894 | 3/20 | 0.41 |
| ▸ | MMP3 | P08254 | 2/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 2/20 | 0.34 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexanol SCHEMBL28571097 | 1.00 | TSHR (0.62) | TSHRMMP2CA12CA1CA2 | |
| Cyclohexanol SCHEMBL27337821 | 1.00 | TSHR (0.62) | TSHRMMP2CA12CA1CA2 | |
| Cyclopentanol SCHEMBL28275625 | 0.97 | TSHR (0.67) | TSHRMMP2CA12CA1CA2 | |
| SCHEMBL11948482 | 0.83 | TSHR (0.91) | TSHRCA1CA2CES2CES1 | |
| SCHEMBL811883 | 0.83 | TSHR (0.91) | TSHRCA1CA2CES2CES1 | |
| SCHEMBL23121456 | 0.83 | TSHR (0.91) | TSHRCA1CA2CES2CES1 | |
| Cyclohexanol SCHEMBL8503956 | 0.83 | TSHR (0.91) | TSHRCA1CA2CES2CES1 | |
| Cyclooctanol SCHEMBL40903 | 0.83 | — | — | |
| SCHEMBL11948880 | 0.83 | TSHR (0.91) | TSHRCA1CA2CES2CES1 | |
| SCHEMBL2197408 | 0.83 | TSHR (0.91) | TSHRCA1CA2CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112981481-B | Ultrathin copper foil and preparation method thereof | 广东嘉元科技股份有限公司 | 2021-12-28 | — | — | CN | claimed |
| CN-112981481-A | Ultrathin copper foil and preparation method thereof | 广东嘉元科技股份有限公司 | 2021-06-18 | — | — | CN | claimed |
| CN-112872293-B | Precoated sand casting process for manufacturing deep hole shaft | 新沂市锡沂高新材料产业技术研究院有限公司 | 2022-05-24 | — | — | CN | disclosed |
| CN-114317135-A | Cleaning agent for solar silicon wafer after texturing and cleaning process thereof | 嘉兴市小辰光伏科技有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-112981481-B | Ultrathin copper foil and preparation method thereof | 广东嘉元科技股份有限公司 | 2021-12-28 | — | — | CN | disclosed |
| CN-112981481-A | Ultrathin copper foil and preparation method thereof | 广东嘉元科技股份有限公司 | 2021-06-18 | — | — | CN | disclosed |
| CN-112872293-A | Precoated sand casting process for manufacturing deep hole shaft | 亚威机械制造(徐州)有限公司 | 2021-06-01 | — | — | CN | disclosed |
| CN-112210270-A | Permeable reactive type rusty coating | 常州市大使涂料有限公司 | 2021-01-12 | — | — | CN | disclosed |