Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 10/20 | 0.55 |
| ▸ | F11 | P03951 | 6/20 | 0.55 |
| ▸ | TPSB2 | P20231 | 5/20 | 0.55 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.55 |
| ▸ | PLG | P00747 | 1/20 | 0.55 |
| ▸ | PLAU | P00749 | 1/20 | 0.55 |
| ▸ | F7 | P08709 | 1/20 | 0.55 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.54 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.54 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.54 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28506911 | 0.85 | FFAR1 (0.57) | PDE4DFFAR1PDE4BTP53MDM2 | |
| SCHEMBL28506917 | 0.85 | MRGPRX4 (0.56) | PTGER1PDE4DFFAR1PDE4BMRGPRX4 | |
| SCHEMBL8065449 | 0.84 | PDE4D (0.63) | PDE4DPDE4B | |
| SCHEMBL28510358 | 0.83 | FFAR1 (0.53) | PTGER1PDE4DFFAR1PDE4BTP53 | |
| SCHEMBL17764240 | 0.82 | CFD (0.75) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL16396497 | 0.82 | CFD (0.75) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL28512707 | 0.80 | PDE4D (0.59) | PDE4DFFAR1PDE4B | |
| SCHEMBL28509052 | 0.79 | RXRA (0.65) | PTGER1PDE4DFFAR1PDE4BTP53 | |
| SCHEMBL28509465 | 0.78 | NR4A2 (0.65) | PTGER1PDE4DTP53MRGPRX4 | |
| SCHEMBL3466382 | 0.77 | PDE4D (0.62) | PDE4DFFAR1PDE4BMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108997122-B | 3-aryl-4-alkoxy benzyl ether derivative and preparation method and application thereof | 南方医科大学 | 2020-12-29 | — | — | CN | claimed |
| CN-108997122-B | 3-aryl-4-alkoxy benzyl ether derivative and preparation method and application thereof | 南方医科大学 | 2020-12-29 | — | — | CN | disclosed |