Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CTSG | P08311 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9313360 | 0.89 | KMT2A (0.47) | NR1I2LMNAADRA2ACYP2D6ACHE | |
| SCHEMBL9314839 | 0.82 | KMT2A (0.45) | NR1I2LMNAADRA2ACYP2D6ACHE | |
| SCHEMBL9313397 | 0.82 | KMT2A (0.50) | LMNAKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL17934459 | 0.78 | KMT2A (0.48) | KMT2AMEN1ALDH1A1HPGDRAB9A | |
| SCHEMBL18650130 | 0.77 | NR4A1 (0.47) | LMNACYP2D6SIGMAR1KMT2AMEN1 | |
| SCHEMBL9312663 | 0.76 | MEN1 (0.43) | NR1I2LMNAADRA2ACYP2D6ACHE | |
| SCHEMBL28042188 | 0.76 | HDAC2 (0.69) | LMNAKMT2AMEN1HPGDRAB9A | |
| SCHEMBL18652132 | 0.75 | NR4A1 (0.52) | LMNACYP2D6SIGMAR1KMT2AMEN1 | |
| SCHEMBL21923501 | 0.75 | MLYCD (0.70) | LMNASIGMAR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL24131098 | 0.74 | F7 (0.56) | KMT2AMEN1CTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113493385-B | Method for synthesizing butenafine hydrochloride | 鲁南制药集团股份有限公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-112209837-B | Synthesis method of bributin hydrochloride | 鲁南制药集团股份有限公司 | 2023-03-24 | — | — | CN | disclosed |
| CN-112209838-B | Preparation method of butenaphthol hydrochloride | 鲁南制药集团股份有限公司 | 2023-02-17 | — | — | CN | disclosed |
| CN-115403485-A | Butenafine intermediate compound | 山东新时代药业有限公司 | 2022-11-29 | — | — | CN | disclosed |
| CN-114369039-A | Preparation method of butenafine intermediate | 鲁南制药集团股份有限公司 | 2022-04-19 | — | — | CN | disclosed |
| CN-113493384-A | Preparation method of butenafine hydrochloride | 鲁南制药集团股份有限公司 | 2021-10-12 | — | — | CN | disclosed |
| CN-113493385-A | Method for synthesizing butenafine hydrochloride | 鲁南制药集团股份有限公司 | 2021-10-12 | — | — | CN | disclosed |
| CN-113493388-A | Synthesis method of butenafine hydrochloride | 鲁南制药集团股份有限公司 | 2021-10-12 | — | — | CN | disclosed |
| CN-112209838-A | Preparation method of butenaphthol hydrochloride | 鲁南制药集团股份有限公司 | 2021-01-12 | — | — | CN | disclosed |
| CN-112209837-A | Synthesis method of butenaphthol hydrochloride | 鲁南制药集团股份有限公司 | 2021-01-12 | — | — | CN | disclosed |