Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CTSG | P08311 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28510216 | 0.89 | NR1I2 (0.56) | KMT2AMEN1ALDH1A1HPGDCTSG | |
| SCHEMBL9313397 | 0.79 | KMT2A (0.50) | KMT2AMEN1ALDH1A1HPGDCTSG | |
| SCHEMBL9313576 | 0.78 | PDK1 (0.49) | KMT2AMEN1HPGDNR1I2LMNA | |
| SCHEMBL18652132 | 0.75 | NR4A1 (0.52) | KMT2AMEN1ALDH1A1HPGDLMNA | |
| SCHEMBL18650130 | 0.74 | NR4A1 (0.47) | KMT2AMEN1ALDH1A1HPGDLMNA | |
| SCHEMBL9312678 | 0.74 | CYP2D6 (0.78) | KMT2AMEN1NR1I2LMNAADRA2A | |
| Hydrochloric Acid SCHEMBL9314916 | 0.73 | LMNA (0.76) | KMT2AMEN1ALDH1A1NR1I2LMNA | |
| SCHEMBL9314839 | 0.72 | KMT2A (0.45) | KMT2AMEN1ALDH1A1HPGDNR1I2 | |
| SCHEMBL24131098 | 0.71 | F7 (0.56) | KMT2AMEN1CTSG | |
| SCHEMBL15849622 | 0.71 | NR4A1 (0.50) | KMT2AMEN1ALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1051702-C | Preparing process of amine derivative and fungusicide containing amine derivative | SCIENT RESEARCH AND PHARMACEUT (JP) | 2000-04-26 | — | — | CN | disclosed |
| US-RE34770-E | 1-benzothiophene derivatives; side effect reduction | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1994-11-01 | — | — | US | disclosed |
| US-5200423-A | AMINE DERIVATIVES, PROCESSES FOR PREPARING THE SAME AND FUNGICIDES CONTAINING THE SAME | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1993-04-06 | — | — | US | disclosed |
| US-5106866-A | Skin disorders | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1992-04-21 | — | — | US | disclosed |
| US-5021458-A | Amine derivatives and fungicides containing the same | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1991-06-04 | — | — | US | disclosed |
| EP-0164697-B1 | AMINE DERIVATIVES, PROCESSES FOR PREPARING THE SAME AND FUNGICIDES CONTAINING THE SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 1990-11-07 | — | — | EP | disclosed |
| EP-0164697-A2 | Amine derivatives, processes for preparing the same and fungicides containing the same | Kaken Pharmaceutical Co., Ltd. (JP) | 1985-12-18 | — | — | EP | disclosed |