Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.31 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL28637725 | 0.91 | ALDH1A1 (0.79) | ALDH1A1TSHRTHRBMGAMGAA | |
| Phosphoric Acid SCHEMBL57398 | 0.91 | ALDH1A1 (0.79) | ALDH1A1TSHRTHRBMGAMGAA | |
| Ethylene Glycol SCHEMBL335787 | 0.91 | ALDH1A1 (0.79) | ALDH1A1TSHRTHRBMGAMGAA | |
| Ethylene Glycol SCHEMBL704710 | 0.91 | ALDH1A1 (0.79) | ALDH1A1TSHRTHRBMGAMGAA | |
| Ethylene Glycol SCHEMBL28057960 | 0.89 | ALDH1A1 (0.75) | ALDH1A1TSHRTHRBMGAMGAA | |
| Ethylene Glycol SCHEMBL21715453 | 0.89 | ALDH1A1 (0.75) | ALDH1A1TSHRTHRBMGAMGAA | |
| Methacrylic Acid SCHEMBL10387701 | 0.84 | ALDH1A1 (0.68) | ALDH1A1TSHRTHRBMGAMGAA | |
| Methacrylic Acid SCHEMBL1291895 | 0.84 | ALDH1A1 (0.68) | ALDH1A1TSHRTHRBMGAMGAA | |
| Methacrylic Acid SCHEMBL27571622 | 0.84 | ALDH1A1 (0.68) | ALDH1A1TSHRTHRBMGAMGAA | |
| 2-Methoxyethanol SCHEMBL335226 | 0.83 | ALDH1A1 (0.65) | ALDH1A1TSHRTHRBMGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112334563-A | Silica scale inhibition using chelants blended with acid and alkylene oxide derived polymeric dispersants | 陶氏环球技术有限责任公司 | 2021-02-05 | — | — | CN | claimed |