Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 10/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28510341 | 1.00 | ACE (0.58) | ACELMNASMN1; SMN2 | |
| SCHEMBL28510339 | 1.00 | ACE (0.58) | ACELMNASMN1; SMN2 | |
| SCHEMBL22457757 | 0.91 | ACE (0.55) | ACELMNA | |
| SCHEMBL6438312 | 0.91 | ACE (0.55) | ACELMNA | |
| SCHEMBL7377534 | 0.88 | LTA4H (0.52) | ACELMNA | |
| SCHEMBL22457522 | 0.87 | ACE (0.51) | ACELMNA | |
| SCHEMBL28506583 | 0.84 | ACE (0.45) | ACELMNASMN1; SMN2 | |
| SCHEMBL22457752 | 0.80 | KLK5 (0.47) | ACE | |
| SCHEMBL25054148 | 0.80 | ACE (0.66) | ACELMNASMN1; SMN2 | |
| SCHEMBL28588288 | 0.80 | ACE (0.66) | ACELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112165938-A | Factor XIIA inhibitors | 利兹大学 | 2021-01-01 | — | — | CN | disclosed |