Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.44 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 9/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.38 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CTH | P32929 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7178599 | 0.88 | HCAR2 (0.39) | TSHRTP53EGLN1EGLN3HCAR2 | |
| SCHEMBL29022873 | 0.87 | HCAR2 (0.44) | TSHRTP53EGLN1EGLN3HCAR2 | |
| SCHEMBL5488527 | 0.87 | — | — | |
| SCHEMBL17049105 | 0.85 | TSHR (0.36) | TSHRTP53EGLN1EGLN3HCAR2 | |
| SCHEMBL3990293 | 0.85 | — | — | |
| SCHEMBL5489821 | 0.85 | — | — | |
| SCHEMBL31250060 | 0.84 | HSD17B10 (0.33) | TSHRTP53EGLN1EGLN3HCAR2 | |
| SCHEMBL131247 | 0.84 | TSHR (0.43) | TSHRTP53EGLN1EGLN3HCAR2 | |
| SCHEMBL7249232 | 0.83 | TSHR (0.41) | TSHRTP53EGLN1EGLN3HCAR2 | |
| SCHEMBL9203010 | 0.81 | HCAR2 (0.57) | TSHRHCAR2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071960-B | Silicon-containing heterocyclic matting agents, compounds and polymers | 富士胶片和光纯药株式会社 | 2021-01-12 | — | — | CN | disclosed |