SCHEMBL7249232

SCHEMBL7249232

O=C(O)C=CCCOC=CC(=O)O

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
GABRR1 P24046 2/20 0.41
GABRR2 P28476 2/20 0.41
BLM P54132 2/20 0.41
GABRR3 A8MPY1 1/20 0.41
LMNA P02545 1/20 0.41
APEX1 P27695 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
TP53 P04637 1/20 0.35
EGLN1 Q9GZT9 1/20 0.35
EGLN3 Q9H6Z9 1/20 0.35
HCAR2 Q8TDS4 5/20 0.33
TBXAS1 P24557 4/20 0.32
CTH P32929 1/20 0.31
PTPN1 P18031 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28510587 0.83 TSHR (0.44) TSHRGABRR1GABRR2BLMGABRR3
SCHEMBL26920801 0.80 ABCC4 (0.39) TSHRGABRR1GABRR2BLMGABRR3
SCHEMBL29064493 0.80 ABCC4 (0.39) TSHRGABRR1GABRR2BLMGABRR3
SCHEMBL9436966 0.78 TSHR (0.46) TSHRGABRR1GABRR2BLMGABRR3
SCHEMBL5488527 0.76
SCHEMBL29022873 0.76 HCAR2 (0.44) TSHRGABRR1GABRR2BLMGABRR3
SCHEMBL8355970 0.76 TSHR (0.44) TSHRGABRR1GABRR2BLMGABRR3
SCHEMBL9748238 0.74
SCHEMBL3990293 0.74
SCHEMBL4888380 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6569916-B2 Reacting 2,4,6-trichloro-1,3,5-triazine with secondary- or tertiary amine, reacting intermediate with sodium mercaptan, then with a thiol, in presence of a mixed catalyst, finally with (meth)acryloyl chloride or allyl bromide, then with base KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2003-05-27 US disclosed
US-20020158352-A1 High refractive index triazine monomer KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2002-10-31 US disclosed
US-6403269-B1 ADDITION-CONDENSATION COPOLYMER COMPRISING POLY(ETHER)URETHANE REACTED WITH HYDROXYALKYL (METH)ACRYLATE EXPOSED TO ACTINIC RADIATION; DURABILITY, QUALITY; FLEXOGRAPHIC PRINTING LEACH DOUGLAS R (US) 2002-06-11 US disclosed
US-6399278-B1 Photosensitive compositions and clean running photopolymer printing plates LEACH DOUGLAS R (US) 2002-06-04 US disclosed
EP-0797791-A4 PHOTOSENSITIVE COMPOSITIONS AND CLEAN RUNNING PHOTOPOLYMER PRINTING PLATES THEREFROM HERCULES INC (US) 1999-06-23 EP disclosed
EP-0797791-A1 PHOTOSENSITIVE COMPOSITIONS AND CLEAN RUNNING PHOTOPOLYMER PRINTING PLATES THEREFROM HERCULES INCORPORATED (US) 1997-10-01 EP disclosed
WO-1996018932-A1 PHOTOSENSITIVE COMPOSITIONS AND CLEAN RUNNING PHOTOPOLYMER PRINTING PLATES THEREFROM MACDERMID IMAGING TECHNOLOGY, INC. (US) 1996-06-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020158352-A1 High refractive index triazine monomer WIZ, MKI67, TERB1 TSHR 1458/4885GABRR1 2064/4885GABRR2 2031/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.