Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUSP3 | P51452 | 1/20 | 0.79 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.79 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.79 |
| ▸ | MAPT | P10636 | 7/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | PHGDH | O43175 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.59 |
| ▸ | GFER | P55789 | 1/20 | 0.59 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28520375 | 0.89 | DUSP3 (0.62) | DUSP3PTPN5PTPN11MAPTALDH1A1 | |
| SCHEMBL683973 | 0.89 | DUSP3 (0.76) | DUSP3PTPN5PTPN11MAPTALDH1A1 | |
| SCHEMBL12746264 | 0.88 | DUSP3 (1.00) | DUSP3PTPN5PTPN11MAPTALDH1A1 | |
| SCHEMBL12746255 | 0.88 | DUSP3 (0.71) | DUSP3PTPN5PTPN11MAPTALDH1A1 | |
| SCHEMBL28508004 | 0.87 | MEN1 (0.73) | DUSP3PTPN5PTPN11MAPTALDH1A1 | |
| SCHEMBL28423202 | 0.86 | DUSP3 (0.75) | DUSP3PTPN5PTPN11MAPTALDH1A1 | |
| SCHEMBL21292850 | 0.86 | DUSP3 (0.82) | DUSP3PTPN5PTPN11MAPTALDH1A1 | |
| SCHEMBL21292847 | 0.86 | DUSP3 (0.82) | DUSP3PTPN5PTPN11MAPTALDH1A1 | |
| SCHEMBL28515473 | 0.85 | SIRT1 (0.70) | MAPTLMNAL3MBTL1SMN1; SMN2MEN1 | |
| SCHEMBL21145695 | 0.85 | DUSP3 (0.84) | DUSP3PTPN5PTPN11MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112079744-A | Aromatic acylhydrazone derivatives and application thereof as NA (adenosine) inhibitor | 湖南大学 | 2020-12-15 | — | — | CN | claimed |
| CN-112079744-B | Aromatic acylhydrazone derivatives and application thereof as NA (adenosine) inhibitor | 湖南大学 | 2021-07-30 | — | — | CN | disclosed |
| CN-112079744-A | Aromatic acylhydrazone derivatives and application thereof as NA (adenosine) inhibitor | 湖南大学 | 2020-12-15 | — | — | CN | disclosed |