Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUSP3 | P51452 | 1/20 | 0.62 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.62 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | PHGDH | O43175 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | ALPL | P05186 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | ALPI | P09923 | 1/20 | 0.58 |
| ▸ | ALPG | P10696 | 1/20 | 0.58 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28508004 | 0.90 | MEN1 (0.73) | DUSP3PTPN5PTPN11MEN1KMT2A | |
| SCHEMBL28510646 | 0.89 | DUSP3 (0.79) | DUSP3PTPN5PTPN11MEN1KMT2A | |
| SCHEMBL17988189 | 0.86 | DUSP3 (0.82) | DUSP3PTPN5PTPN11MEN1KMT2A | |
| SCHEMBL28510680 | 0.83 | MAPT (0.62) | DUSP3PTPN5PTPN11MEN1KMT2A | |
| SCHEMBL28511998 | 0.83 | MAPT (0.61) | DUSP3PTPN5PTPN11MEN1KMT2A | |
| SCHEMBL28519354 | 0.83 | KMT2A (0.72) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL12387760 | 0.81 | KMT2A (0.71) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL21211496 | 0.81 | KMT2A (0.71) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL28528684 | 0.81 | SIRT1 (0.80) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL28511869 | 0.80 | MAPT (0.59) | DUSP3PTPN5PTPN11MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112079744-B | Aromatic acylhydrazone derivatives and application thereof as NA (adenosine) inhibitor | 湖南大学 | 2021-07-30 | — | — | CN | disclosed |
| CN-112079744-A | Aromatic acylhydrazone derivatives and application thereof as NA (adenosine) inhibitor | 湖南大学 | 2020-12-15 | — | — | CN | disclosed |