SCHEMBL28511307

SCHEMBL28511307

Clc1cc2ccc1COC2

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
MAPT P10636 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
PRKCG P05129 1/20 0.30
PRKCA P17252 1/20 0.30
PRKCD Q05655 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29026587 0.75 PRKCG (0.37) KDM4EMAPTL3MBTL1PRKCGPRKCA
SCHEMBL28514559 0.69 KDM4E (0.39) KDM4EMAPTL3MBTL1PRKCGPRKCA
SCHEMBL9613115 0.69 HTR2A (0.32)
SCHEMBL6929056 0.68
SCHEMBL30068612 0.67 HTR2A (0.45) KDM4EMAPTL3MBTL1
SCHEMBL3218240 0.67 HTR2A (0.45) KDM4EMAPTL3MBTL1
SCHEMBL6933805 0.64
Benzene SCHEMBL29093801 0.63 LMNA (0.31)
SCHEMBL4971713 0.62 PRKCG (0.41) PRKCGPRKCAPRKCD
SCHEMBL18150831 0.61 NOTUM (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110407663-B Dechlorination method of chlorine-containing aromatic compound 厦门大学 2021-01-26 CN claimed
CN-116354800-A Production method of 2, 5-dichloro-p-xylylene ether 浙江东海新材料科技股份有限公司 2023-06-30 CN disclosed
CN-110407663-B Dechlorination method of chlorine-containing aromatic compound 厦门大学 2021-01-26 CN disclosed