Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21719252 | 0.80 | — | — | |
| SCHEMBL15543642 | 0.79 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL21719411 | 0.78 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL15471375 | 0.76 | ALDH1A1 (0.41) | ALDH1A1MAPKAPK2 | |
| SCHEMBL21719232 | 0.75 | SIRT6 (0.31) | ALDH1A1 | |
| SCHEMBL10139091 | 0.75 | KDM4E (0.32) | ALDH1A1 | |
| SCHEMBL18923847 | 0.74 | MAPKAPK2 (0.39) | ALDH1A1MAPKAPK2 | |
| SCHEMBL25325432 | 0.74 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL19238969 | 0.71 | ALDH1A1 (0.36) | ALDH1A1MAPKAPK2 | |
| Hydrochloric Acid SCHEMBL19206189 | 0.70 | ALDH1A1 (0.35) | ALDH1A1MAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114072404-A | RET selective inhibitor and preparation method and application thereof | 首药控股(北京)股份有限公司 | 2022-02-18 | — | — | CN | disclosed |
| CN-112209925-A | RET selective inhibitor and preparation method and application thereof | 首药控股(北京)有限公司 | 2021-01-12 | — | — | CN | disclosed |