Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20242474 | 0.79 | MAPT (0.57) | ALDH1A1KMT2AMEN1HTTMAPT | |
| SCHEMBL3564275 | 0.78 | MEN1 (0.66) | KDM4EALDH1A1KMT2AMEN1POLB | |
| SCHEMBL29789626 | 0.78 | MEN1 (0.66) | KDM4EALDH1A1KMT2AMEN1POLB | |
| SCHEMBL9260905 | 0.77 | ALDH1A1 (0.45) | KDM4EALDH1A1KMT2AMEN1POLB | |
| SCHEMBL14247603 | 0.77 | KDM4E (0.45) | KDM4EALDH1A1KMT2AMEN1POLB | |
| SCHEMBL23316710 | 0.76 | POLB (0.53) | KDM4EALDH1A1KMT2AMEN1POLB | |
| SCHEMBL20259851 | 0.76 | MAPT (0.56) | ALDH1A1KMT2AMEN1HTTMAPT | |
| SCHEMBL20241865 | 0.76 | MAPT (0.56) | ALDH1A1KMT2AMEN1HTTMAPT | |
| SCHEMBL9609035 | 0.75 | KDM4E (0.51) | KDM4EALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL4077406 | 0.73 | MAPK1 (0.62) | ALDH1A1KMT2AMEN1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111704579-B | Benzimidazole compound synthesis method based on iron-catalyzed redox coupling reaction | 中国农业大学 | 2021-12-14 | — | — | CN | disclosed |
| CN-111704579-A | Benzimidazole compound synthesis method based on iron-catalyzed redox coupling reaction | 中国农业大学 | 2020-09-25 | — | — | CN | disclosed |