Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | FADS1 | O60427 | 1/20 | 0.40 |
| ▸ | BRS3 | P32247 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 2/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.38 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14247603 | 0.78 | KDM4E (0.45) | ALDH1A1KDM4EPRKCQCA1CA2 | |
| SCHEMBL28511892 | 0.77 | KDM4E (0.64) | ALDH1A1KDM4EMEN1KMT2APOLB | |
| SCHEMBL28058849 | 0.76 | MAPT (0.49) | ALDH1A1MEN1KMT2APOLBMAPK1 | |
| SCHEMBL8543534 | 0.74 | PRKCQ (0.51) | ALDH1A1KDM4EPRKCQCA1CA2 | |
| SCHEMBL11118897 | 0.72 | PDPK1 (0.56) | ALDH1A1KDM4ECA1CA2PDPK1 | |
| SCHEMBL20242526 | 0.72 | MAPT (0.60) | ALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL2905886 | 0.71 | PRKCQ (0.48) | ALDH1A1KDM4EPRKCQPDPK1MEN1 | |
| SCHEMBL2905882 | 0.71 | PRKCQ (0.48) | ALDH1A1KDM4EPRKCQPDPK1MEN1 | |
| SCHEMBL30806338 | 0.71 | MEN1 (0.46) | ALDH1A1KDM4EPRKCQCA1CA2 | |
| SCHEMBL4217697 | 0.71 | CTSV (0.54) | ALDH1A1KDM4EMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5405856-A | Skin disorders | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-04-11 | — | — | US | claimed |
| US-5405856-A | Skin disorders | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-04-11 | — | — | US | disclosed |
| US-5221682-A | Skin disorders | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-06-22 | — | — | US | disclosed |
| US-5034403-A | Topical antiinflammatory agents for skin disorders | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1991-07-23 | — | — | US | disclosed |
| US-4983615-A | ANTIINFLAMMATORY AGENTS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1991-01-08 | — | — | US | disclosed |
| EP-0405425-A2 | Heteroarylamino- and heteroaryloxypyridinamines and related compounds, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-01-02 | — | — | EP | disclosed |
| US-4970219-A | TOPICAL ANTIINFLAMMATORY AGENTS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1990-11-13 | — | — | US | disclosed |