Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29283274 | 0.89 | LSS (0.48) | MEN1KMT2ASMN1; SMN2PRSS1HTT | |
| SCHEMBL28993960 | 0.83 | NPC1 (0.50) | MEN1KMT2ALMNAPARP10MAPT | |
| SCHEMBL28675818 | 0.83 | PARP10 (0.49) | LMNAPARP10PRSS1 | |
| SCHEMBL25350769 | 0.82 | APP (0.55) | MEN1KMT2ALMNAPARP10MAPT | |
| SCHEMBL881472 | 0.81 | L3MBTL1 (0.58) | MEN1KMT2AL3MBTL1PARP10MAPT | |
| SCHEMBL5703994 | 0.81 | PARP10 (0.47) | MEN1KMT2ALMNAPARP10MAPT | |
| SCHEMBL4763622 | 0.81 | MEN1 (0.56) | MEN1KMT2ARECQLLMNAL3MBTL1 | |
| SCHEMBL16502888 | 0.81 | MEN1 (0.54) | MEN1KMT2ALMNAL3MBTL1PARP10 | |
| SCHEMBL6677595 | 0.81 | PARP10 (0.65) | MEN1KMT2ARECQLLMNAPARP10 | |
| SCHEMBL17466900 | 0.80 | MEN1 (0.59) | MEN1KMT2ARECQLLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115298182-A | Fused pyrimidine compounds as KCC2 modulators | 阿斯利康(瑞典)有限公司 | 2022-11-04 | — | — | CN | disclosed |
| CN-112243439-A | Pyrrolo [2,3-B ] pyridines or pyrrolo [2,3-B ] pyrazines as HPK1 inhibitors and uses thereof | 百济神州有限公司 | 2021-01-19 | — | — | CN | disclosed |