Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.49 |
| ▸ | LTA4H | P09960 | 3/20 | 0.47 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6680689 | 0.90 | NR1H2 (0.44) | PARP10LTA4HNR5A1PRSS1LMNA | |
| SCHEMBL6683181 | 0.89 | GAA (0.50) | PARP10CYP19A1PKM | |
| SCHEMBL29226861 | 0.87 | ESR1 (0.47) | LTA4HLMNAESR1ESR2 | |
| SCHEMBL28993960 | 0.85 | NPC1 (0.50) | PARP10PRSS1LMNAAPPPKM | |
| SCHEMBL5703994 | 0.83 | PARP10 (0.47) | PARP10PRSS1LMNAAPPPKM | |
| SCHEMBL881472 | 0.83 | L3MBTL1 (0.58) | PARP10 | |
| SCHEMBL28512110 | 0.83 | MEN1 (0.56) | PARP10PRSS1LMNA | |
| SCHEMBL16502888 | 0.83 | MEN1 (0.54) | PARP10PRSS1LMNA | |
| SCHEMBL6677595 | 0.82 | PARP10 (0.65) | PARP10LMNAPKM | |
| SCHEMBL28462539 | 0.81 | PARP10 (0.46) | PARP10PRSS1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113801094-A | 2-carbonyl benzothiophene compound and preparation method and application thereof | 中国药科大学 | 2021-12-17 | — | — | CN | disclosed |