Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.37 |
| ▸ | GABRE | P78334 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28512646 | 0.81 | TDP1 (0.42) | HPGDTDP1GPR3MEN1KMT2A | |
| SCHEMBL28356006 | 0.81 | TDP1 (0.46) | HPGDTDP1GPR3ITGA4MEN1 | |
| SCHEMBL28906614 | 0.81 | HPGD (0.46) | HPGDTDP1SLC9A1LMNAGPR3 | |
| SCHEMBL28507957 | 0.81 | HPGD (0.43) | HPGDTDP1GABRPGABRDGABRA1 | |
| SCHEMBL28521257 | 0.81 | SLC9A1 (0.39) | HPGDSLC9A1HSD17B1HSD17B2KDM4E | |
| SCHEMBL28512211 | 0.81 | HPGD (0.43) | HPGDTDP1SLC9A1KDM4EGABRP | |
| SCHEMBL15200639 | 0.78 | SLC9A1 (0.40) | HPGDSLC9A1HSD17B1HSD17B2KDM4E | |
| SCHEMBL1518886 | 0.76 | GPR3 (0.55) | HPGDTDP1KDM4EGPR3MEN1 | |
| SCHEMBL29014457 | 0.75 | HPGD (0.47) | HPGDTDP1HSD17B1HSD17B2KDM4E | |
| SCHEMBL30326126 | 0.75 | HPGD (0.47) | HPGDTDP1HSD17B1HSD17B2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110656346-B | Method for continuously preparing 2-aryl-3-halogenated-benzothiophene compound by using electrochemical microchannel reaction device | 南京工业大学 | 2021-02-02 | — | — | CN | disclosed |
| CN-110656346-A | Method for continuously preparing 2-aryl-3-halogenated-benzothiophene compound by using electrochemical microchannel reaction device | 南京工业大学 | 2020-01-07 | — | — | CN | disclosed |