Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 3/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29264501 | 0.80 | MEN1 (0.45) | MEN1NPC1KMT2ASMN1; SMN2P2RX7 | |
| SCHEMBL12388043 | 0.75 | P2RX7 (0.39) | MEN1KMT2AARSMN1; SMN2P2RX7 | |
| SCHEMBL7691409 | 0.71 | ALDH1A1 (0.50) | MEN1NPC1KMT2ASMN1; SMN2NOS2 | |
| SCHEMBL15669988 | 0.70 | SMN1; SMN2 (0.54) | MEN1KMT2ASMN1; SMN2P2RX7GAA | |
| SCHEMBL3258945 | 0.69 | MEN1 (0.47) | MEN1KMT2ASMN1; SMN2P2RX7KDM4E | |
| SCHEMBL2844976 | 0.69 | SMN1; SMN2 (0.41) | MEN1NPC1KMT2ASMN1; SMN2P2RX7 | |
| SCHEMBL3258947 | 0.69 | MEN1 (0.47) | MEN1KMT2ASMN1; SMN2P2RX7KDM4E | |
| SCHEMBL3259222 | 0.69 | MEN1 (0.47) | MEN1KMT2ASMN1; SMN2P2RX7KDM4E | |
| SCHEMBL3257578 | 0.69 | MEN1 (0.47) | MEN1KMT2ASMN1; SMN2P2RX7KDM4E | |
| SCHEMBL2724030 | 0.69 | SMN1; SMN2 (0.52) | MEN1KMT2ASMN1; SMN2P2RX7GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111792999-B | Dinaphthylamine compounds, and preparation method and application thereof | 五邑大学 | 2022-08-09 | — | — | CN | disclosed |
| CN-111792999-A | Dinaphthylamine compounds, and preparation method and application thereof | 五邑大学 | 2020-10-20 | — | — | CN | disclosed |