Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.58 |
| ▸ | HRH2 | P25021 | 1/20 | 0.55 |
| ▸ | HRH1 | P35367 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | PLK1 | P53350 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3031629 | 0.83 | TP53 (0.62) | HRH2HRH1PLA2G4BL3MBTL1GAA | |
| SCHEMBL3830886 | 0.81 | HDAC3 (0.61) | NPC1ALDH1A1PARP10MAPTRECQL | |
| SCHEMBL7627400 | 0.81 | NPC1 (0.72) | NPC1NPSR1HPGDALDH1A1PARP10 | |
| SCHEMBL6317361 | 0.81 | NPC1 (0.72) | NPC1NPSR1HPGDALDH1A1PARP10 | |
| SCHEMBL1811144 | 0.80 | L3MBTL1 (0.58) | NPC1ALDH1A1HRH2HRH1MAPT | |
| SCHEMBL14518784 | 0.80 | ALDH1A1 (0.53) | NPC1HPGDALDH1A1MAPTPOLB | |
| Hydrochloric Acid SCHEMBL28047842 | 0.80 | HDAC3 (0.59) | NPC1ALDH1A1PARP10MAPTRECQL | |
| SCHEMBL6577306 | 0.79 | NPC1 (0.70) | NPC1NPSR1HPGDALDH1A1PARP10 | |
| SCHEMBL948187 | 0.79 | GAA (0.62) | NPC1NPSR1HPGDALDH1A1PARP10 | |
| SCHEMBL19043134 | 0.79 | HRH2 (0.50) | NPSR1ALDH1A1HRH2HRH1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112321440-B | Amino phenyl ketone compound and preparation method and application thereof | 南方医科大学 | 2021-09-24 | — | — | CN | disclosed |
| CN-112321440-A | Amino phenyl ketone compound and preparation method and application thereof | 南方医科大学 | 2021-02-05 | — | — | CN | disclosed |