Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 6/20 | 0.61 |
| ▸ | CASP6 | P55212 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | GAA | P10253 | 6/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 6/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.57 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3334063 | 0.87 | GFER (0.65) | GFERCASP6MAPTGAAALOX15 | |
| SCHEMBL30722331 | 0.84 | ITGB3 (0.62) | GFERCASP6MAPTGAAALOX15 | |
| SCHEMBL1433124 | 0.84 | AOC3 (0.72) | CYP17A1CYP21A2CYP11B1RORCAOC3 | |
| SCHEMBL764335 | 0.83 | MAPT (0.76) | GFERCASP6MAPTGAAALOX15 | |
| SCHEMBL20346925 | 0.82 | GFER (0.68) | GFERCASP6MAPTGAAALOX15 | |
| SCHEMBL20424995 | 0.81 | GFER (0.61) | GFERCASP6MAPTGAAALOX15 | |
| SCHEMBL23355487 | 0.80 | MAPT (0.61) | MAPTGAAKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL15392533 | 0.80 | CHKA (0.65) | GFERMAPTGAAKDM4ESMN1; SMN2 | |
| SCHEMBL20306323 | 0.79 | GFER (0.59) | GFERCASP6MAPTGAAALOX15 | |
| SCHEMBL30754206 | 0.79 | GFER (0.64) | GFERCASP6MAPTGAAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112423758-A | Adenosine receptor binding compounds | 尼康治疗公司 | 2021-02-26 | — | — | CN | disclosed |