Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 5/20 | 0.65 |
| ▸ | CASP6 | P55212 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 8/20 | 0.59 |
| ▸ | GAA | P10253 | 6/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 6/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.59 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | CHKA | P35790 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28512583 | 0.87 | GFER (0.61) | GFERCASP6MAPTGAAALOX15 | |
| SCHEMBL764335 | 0.86 | MAPT (0.76) | GFERCASP6MAPTGAAALOX15 | |
| SCHEMBL20346925 | 0.85 | GFER (0.68) | GFERCASP6MAPTGAAALOX15 | |
| SCHEMBL1136936 | 0.84 | CHKA (0.54) | GFERMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL20424995 | 0.83 | GFER (0.61) | GFERCASP6MAPTGAAALOX15 | |
| SCHEMBL30754206 | 0.82 | GFER (0.64) | GFERCASP6MAPTGAAALOX15 | |
| SCHEMBL20306323 | 0.82 | GFER (0.59) | GFERCASP6MAPTGAAALOX15 | |
| SCHEMBL19696932 | 0.82 | GFER (0.59) | GFERCASP6MAPTGAAALOX15 | |
| SCHEMBL1433159 | 0.81 | AOC3 (0.72) | RORC | |
| SCHEMBL13061748 | 0.81 | MAPT (0.69) | GFERCASP6MAPTGAAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100143455-A1 | Triazole antifungal agents | WU NIAN | 2010-06-10 | — | — | US | disclosed |
| US-20090233843-A1 | METHODS AND COMPOSITIONS FOR TREATING DIABETES, METABOLIC SYNDROME AND OTHER CONDITIONS | CORTENDO INVEST AB (SE) | 2009-09-17 | — | — | US | disclosed |
| US-7160877-B2 | Aliphatic nitrogen-containing 5-membered ring compound | TANABE SEIYAKU CO., LTD. (JP) | 2007-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233843-A1 | METHODS AND COMPOSITIONS FOR TREATING DIABETES, METABOLIC SYNDROME AND OTHER CONDITIONS | CYP11B2, HSD3B2, HSD3B1 | GFER 3782/4885CASP6 4430/4885MAPT 916/4885 |
| US-20100143455-A1 | Triazole antifungal agents | CYP3A7, ERG28, UGT1A7 | GFER 2320/4885CASP6 1074/4885MAPT 1110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.